fenbendazole has been researched along with Cancer of Ovary in 3 studies
Fenbendazole: Antinematodal benzimidazole used in veterinary medicine.
fenbendazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to inhibit ovarian cancer (OC) development by interfering with microtubule polymerization and inhibiting mTOR signaling." | 1.91 | Anticancer Evaluation of Methoxy Poly(Ethylene Glycol)- ( Choi, JY; Lee, JW; Shin, DH; Shin, YB, 2023) |
| "Fenbendazole (FZ) has potential anti-cancer effects, but its poor water solubility limits its use for cancer therapy." | 1.91 | Anti-cancer effect of fenbendazole-incorporated PLGA nanoparticles in ovarian cancer. ( Chang, CS; Cho, YJ; Choi, JJ; Choi, JK; Choi, JY; Han, HD; Hwang, JR; Lee, CM; Lee, JW; Noh, JJ; Ryu, JY; Won, JE, 2023) |
| "Mebendazole was evaluated in cisplatin-resistant high grade serous stage 3C ovarian cancer patient derived xenograft (PDX) models: PDX-0003 (p53 null) and PDX-0030 (p53 positive), and on ovarian cancer cell lines: MES-OV (p53 R282W), ES2 (p53 S241F), A2780 (p53 wild type), SKOV3 parental (p53 null) and isogenic sublines, SKOV3 R273H p53 and SKOV3 R248W p53." | 1.62 | Potential and mechanism of mebendazole for treatment and maintenance of ovarian cancer. ( Benbrook, DM; Bieniasz, M; Elayapillai, S; Gunderson, CC; Hunsucker, LA; Isingizwe, ZR; Kennedy, AL; Lightfoot, S; Pathuri, G; Ramraj, S; Wang, L; Zhao, YD, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, YB | 1 |
| Choi, JY | 2 |
| Shin, DH | 1 |
| Lee, JW | 2 |
| Chang, CS | 1 |
| Ryu, JY | 1 |
| Choi, JK | 1 |
| Cho, YJ | 1 |
| Choi, JJ | 1 |
| Hwang, JR | 1 |
| Noh, JJ | 1 |
| Lee, CM | 1 |
| Won, JE | 1 |
| Han, HD | 1 |
| Elayapillai, S | 1 |
| Ramraj, S | 1 |
| Benbrook, DM | 1 |
| Bieniasz, M | 1 |
| Wang, L | 1 |
| Pathuri, G | 1 |
| Isingizwe, ZR | 1 |
| Kennedy, AL | 1 |
| Zhao, YD | 1 |
| Lightfoot, S | 1 |
| Hunsucker, LA | 1 |
| Gunderson, CC | 1 |
3 other studies available for fenbendazole and Cancer of Ovary
| Article | Year |
|---|---|
Anticancer Evaluation of Methoxy Poly(Ethylene Glycol)-
Topics: Cell Line, Tumor; Drug Carriers; Female; Fenbendazole; Humans; Micelles; Ovarian Neoplasms; Polyeste | 2023 |
Anti-cancer effect of fenbendazole-incorporated PLGA nanoparticles in ovarian cancer.
Topics: Animals; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Female; Fenbendazole; Humans; Mice; Nanopa | 2023 |
Potential and mechanism of mebendazole for treatment and maintenance of ovarian cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Drug Repositioning; Drug | 2021 |