fenamic acid has been researched along with Kidney Papillary Necrosis in 3 studies
fenamic acid: has chloride and potassium channel-blocking activity; RN given refers to parent cpd
fenamic acid : An aminobenzoic acid that is the N-phenyl derivative of anthranilic acid. It acts as a parent skeleton for the synthesis of several non-steroidal anti-inflammatory drugs.
Kidney Papillary Necrosis: A complication of kidney diseases characterized by cell death involving KIDNEY PAPILLA in the KIDNEY MEDULLA. Damages to this area may hinder the kidney to concentrate urine resulting in POLYURIA. Sloughed off necrotic tissue may block KIDNEY PELVIS or URETER. Necrosis of multiple renal papillae can lead to KIDNEY FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " When untreated rats were dosed orally with NH4Cl (400 mg/kg) there was a lag period between 0 and 2 hr (when no changes in H+ excretion occurred), but the urinary pH was depressed in the 2- to 4-hr collection period." | 1.27 | The effect of N-phenylanthranilic acid-induced renal papillary necrosis on urinary acidification and renal electrolyte handling. ( Bach, PH; Hardy, TL, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, YX | 1 |
| Betton, G | 1 |
| Floettmann, E | 1 |
| Liess, C | 1 |
| Hardy, TL | 1 |
| Bach, PH | 2 |
| Nguyen, TK | 1 |
| Obatomi, DK | 1 |
3 other studies available for fenamic acid and Kidney Papillary Necrosis
| Article | Year |
|---|---|
MRI histopathology correlation of N-phenylanthranilic acid induced nephropathy in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Kidney; Kidney Diseases; Kidney Papillary Necrosis | 2006 |
The effect of N-phenylanthranilic acid-induced renal papillary necrosis on urinary acidification and renal electrolyte handling.
Topics: Administration, Oral; Ammonium Chloride; Animals; Blood Urea Nitrogen; Chlorides; Hydrogen-Ion Conce | 1984 |
Increased urinary uronic acid excretion in experimentally-induced renal papillary necrosis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Creatinine; Kidney Papillary Necrosis; | 2001 |