felodipine has been researched along with Pregnancy in 7 studies
Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.
felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report three cases of felodipine use in pregnancy by women with chronic hypertension." | 7.69 | Felodipine use in pregnancy. Report of three cases. ( Casele, HL; Gratton, R; Laifer, SA; Prieto, JA; Windley, KC, 1997) |
| "We report three cases of felodipine use in pregnancy by women with chronic hypertension." | 3.69 | Felodipine use in pregnancy. Report of three cases. ( Casele, HL; Gratton, R; Laifer, SA; Prieto, JA; Windley, KC, 1997) |
| "In a recent study, the vasodilating drugs nifedipine, nitrendipine, felodipine, and hydralazine induced phalangeal defects in rabbits, when given on day 16 of pregnancy." | 3.68 | Histological and in vitro studies supporting decreased uteroplacental blood flow as explanation for digital defects after administration of vasodilators. ( Danielson, M; Danielsson, BR; Dencker, L; Regård, CG; Reiland, S; Rundqvist, E, 1990) |
| " In fertility, teratology and peri-postnatal studies Sprague-Dawley rats were dosed by gavage with 10, 25 and 70 mumol/kg (fertility and teratology studies) or 3, 10 and 30 mumol/kg (peri-postnatal study)." | 1.29 | Reproductive toxicity studies of the antihypertensive agent felodipine in the rat. ( Danielson, MK; Danielsson, BR, 1993) |
| "Monensin prevented the increase in thromboplastin activity at 68 hr as well as at 90-96 hr." | 1.27 | Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo. ( Dalaker, K; Prydz, H, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Danielson, MK | 1 |
| Danielsson, BR | 2 |
| Casele, HL | 1 |
| Windley, KC | 1 |
| Prieto, JA | 1 |
| Gratton, R | 1 |
| Laifer, SA | 1 |
| Lundgren, Y | 1 |
| Thalén, P | 1 |
| Nordlander, M | 1 |
| Danielson, M | 1 |
| Reiland, S | 1 |
| Rundqvist, E | 1 |
| Dencker, L | 1 |
| Regård, CG | 1 |
| Dalaker, K | 1 |
| Prydz, H | 1 |
| Lechner, W | 1 |
| Keene, F | 1 |
| Marth, C | 1 |
| Zech, J | 1 |
7 other studies available for felodipine and Pregnancy
| Article | Year |
|---|---|
Reproductive toxicity studies of the antihypertensive agent felodipine in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Felodipine; Female; Fertility; Fetus; Labor, Obst | 1993 |
Felodipine use in pregnancy. Report of three cases.
Topics: Adult; Calcium Channel Blockers; Felodipine; Female; Follow-Up Studies; Humans; Hypertension; Infant | 1997 |
Cutaneous drug reaction case reports: from the world literature.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Bupropion; Celecoxib; Chlorquinaldol; Cytarabi | 2002 |
Effects of felodipine on utero-placental blood flow in normotensive rabbits.
Topics: Administration, Oral; Animals; Blood Pressure; Felodipine; Female; Heart Rate; Placenta; Pregnancy; | 1992 |
Histological and in vitro studies supporting decreased uteroplacental blood flow as explanation for digital defects after administration of vasodilators.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Extremities; Felodipine; Female; In Vitro Techni | 1990 |
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Fe | 1986 |
Calcium and calmodulin antagonism for inhibition of uterine contractions.
Topics: Calcium; Calmodulin; Culture Techniques; Diltiazem; Felodipine; Female; Humans; Nitrendipine; Pregna | 1989 |