felodipine has been researched along with Necrosis in 2 studies
Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.
felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of the vasoselective calcium antagonist felodipine on myocardial necrosis was studied in 14 anesthetized pigs subjected to 45-min occlusion of the left anterior descending coronary artery (LAD) followed by 24-h reperfusion." | 7.68 | Coronary venous retroinfusion of felodipine reduces myocardial necrosis after coronary occlusion and reperfusion. ( Haga, Y; Hatori, N; Nordlander, M; Rydén, L; Sjöquist, PO, 1993) |
| "Felodipine has a protective effect on the myocardium and kidney as evidenced by decreased perivascular inflammation, myocardial necrosis and fibrosis." | 5.36 | Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats. ( Franco, M; Janicki, JS; Matsubara, BB; Matsubara, LS, 2010) |
| "The effect of the vasoselective calcium antagonist felodipine on myocardial necrosis was studied in 14 anesthetized pigs subjected to 45-min occlusion of the left anterior descending coronary artery (LAD) followed by 24-h reperfusion." | 3.68 | Coronary venous retroinfusion of felodipine reduces myocardial necrosis after coronary occlusion and reperfusion. ( Haga, Y; Hatori, N; Nordlander, M; Rydén, L; Sjöquist, PO, 1993) |
| "Felodipine has a protective effect on the myocardium and kidney as evidenced by decreased perivascular inflammation, myocardial necrosis and fibrosis." | 1.36 | Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats. ( Franco, M; Janicki, JS; Matsubara, BB; Matsubara, LS, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsubara, BB | 1 |
| Franco, M | 1 |
| Janicki, JS | 1 |
| Matsubara, LS | 1 |
| Hatori, N | 1 |
| Haga, Y | 1 |
| Sjöquist, PO | 1 |
| Nordlander, M | 1 |
| Rydén, L | 1 |
2 other studies available for felodipine and Necrosis
| Article | Year |
|---|---|
Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats.
Topics: Aldosterone; Animals; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Felodipine; | 2010 |
Coronary venous retroinfusion of felodipine reduces myocardial necrosis after coronary occlusion and reperfusion.
Topics: Animals; Coronary Vessels; Felodipine; Female; Hemodynamics; Infusions, Intravenous; Male; Myocardia | 1993 |