felodipine has been researched along with Metabolic Syndrome in 3 studies
Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.
felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.
Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metabolic syndrome is associated with an increased incidence of atherosclerosis." | 5.35 | Felodipine attenuates vascular inflammation in a fructose-induced rat model of metabolic syndrome via the inhibition of NF-kappaB activation. ( Bi, XP; Gong, HP; Li, L; Tan, HW; Xing, SS; Zhang, W; Zhang, Y; Zhong, M, 2008) |
| "Felodipine (5 mg/kg/d) was then administered by gavage daily for 6 weeks to the felodipine group." | 5.35 | Felodipine downregulates serum interleukin-18 levels in rats with fructose-induced metabolic syndrome. ( Bi, XP; Tan, HW; Xing, SS; Zhang, W; Zhang, Y; Zhong, M, 2009) |
| "Metabolic syndrome is associated with an increased incidence of atherosclerosis." | 1.35 | Felodipine attenuates vascular inflammation in a fructose-induced rat model of metabolic syndrome via the inhibition of NF-kappaB activation. ( Bi, XP; Gong, HP; Li, L; Tan, HW; Xing, SS; Zhang, W; Zhang, Y; Zhong, M, 2008) |
| "Felodipine (5 mg/kg/d) was then administered by gavage daily for 6 weeks to the felodipine group." | 1.35 | Felodipine downregulates serum interleukin-18 levels in rats with fructose-induced metabolic syndrome. ( Bi, XP; Tan, HW; Xing, SS; Zhang, W; Zhang, Y; Zhong, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tan, HW | 2 |
| Xing, SS | 2 |
| Bi, XP | 2 |
| Li, L | 1 |
| Gong, HP | 1 |
| Zhong, M | 2 |
| Zhang, Y | 2 |
| Zhang, W | 2 |
| Miczke, A | 1 |
| Pupek-Musialik, D | 1 |
| Cymerys, M | 1 |
| Bryl, W | 1 |
| Kujawska-Łuczak, M | 1 |
| Bogdański, P | 1 |
1 trial available for felodipine and Metabolic Syndrome
| Article | Year |
|---|---|
[The effect of analysed hypotensive drugs on certain metabolic parameters].
Topics: Adult; Antihypertensive Agents; Diabetes Mellitus, Type 2; Felodipine; Female; Humans; Hyperlipidemi | 2003 |
2 other studies available for felodipine and Metabolic Syndrome
| Article | Year |
|---|---|
Felodipine attenuates vascular inflammation in a fructose-induced rat model of metabolic syndrome via the inhibition of NF-kappaB activation.
Topics: Animals; Biotransformation; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Cell Adhesion M | 2008 |
Felodipine downregulates serum interleukin-18 levels in rats with fructose-induced metabolic syndrome.
Topics: Animal Feed; Animals; Blood Glucose; Blood Pressure; Body Weight; Calcium Channel Blockers; Choleste | 2009 |