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felodipine and Lung Diseases, Obstructive

felodipine has been researched along with Lung Diseases, Obstructive in 7 studies

Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.
felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.

Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.

Research Excerpts

ExcerptRelevanceReference
"In 10 patients with advanced chronic lung disease and pulmonary hypertension central haemodynamics and pulmonary gas exchange were studied at rest and during exercise, before and during continuous infusion of the calcium antagonist felodipine, which lowers vascular resistance by selective action on vascular smooth muscle."7.67The effect of a new calcium antagonist, felodipine, on pulmonary hypertension and gas exchange in chronic obstructive lung disease. ( Bratel, T; Hedenstierna, G; Nyquist, O; Ripe, E, 1985)
"In 10 patients with advanced chronic lung disease and pulmonary hypertension central haemodynamics and pulmonary gas exchange were studied at rest and during exercise, before and during continuous infusion of the calcium antagonist felodipine, which lowers vascular resistance by selective action on vascular smooth muscle."3.67The effect of a new calcium antagonist, felodipine, on pulmonary hypertension and gas exchange in chronic obstructive lung disease. ( Bratel, T; Hedenstierna, G; Nyquist, O; Ripe, E, 1985)
" We have compared the pulmonary vasodilator effects, dose-response characteristics, and tolerability of two calcium channel blockers, amlodipine and extended-release (ER) felodipine, in 10 patients (seven men, age 68+/-4."2.68A comparison of two long-acting vasoselective calcium antagonists in pulmonary hypertension secondary to COPD. ( Alpers, JA; Bune, AJ; Frith, PA; McEvoy, RD; Sajkov, D; Wang, T, 1997)
" Further dosage adjustments are made in accordance with a set protocol."2.67The Hypertension Optimal Treatment (HOT) Study--patient characteristics: randomization, risk profiles, and early blood pressure results. ( Hansson, L; Zanchetti, A, 1994)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's4 (57.14)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansson, L1
Zanchetti, A1
Sajkov, D2
McEvoy, RD2
Cowie, RJ1
Bradley, JA1
Antic, R1
Morris, RG1
Frith, PA2
Wang, T1
Bune, AJ1
Alpers, JA1
Bratel, T4
Hedenstierna, G4
Nyquist, O4
Ripe, E4
Lundquist, H1

Trials

2 trials available for felodipine and Lung Diseases, Obstructive

ArticleYear
The Hypertension Optimal Treatment (HOT) Study--patient characteristics: randomization, risk profiles, and early blood pressure results.
    Blood pressure, 1994, Volume: 3, Issue:5

    Topics: Adrenergic beta-Antagonists; Age Distribution; Aged; Aged, 80 and over; Angiotensin-Converting Enzym

1994
A comparison of two long-acting vasoselective calcium antagonists in pulmonary hypertension secondary to COPD.
    Chest, 1997, Volume: 111, Issue:6

    Topics: Aged; Amlodipine; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Dose-Re

1997

Other Studies

5 other studies available for felodipine and Lung Diseases, Obstructive

ArticleYear
Felodipine improves pulmonary hemodynamics in chronic obstructive pulmonary disease.
    Chest, 1993, Volume: 103, Issue:5

    Topics: Aged; Blood Pressure; Cardiac Output; Echocardiography, Doppler; Felodipine; Female; Humans; Hyperte

1993
The use of a vasodilator, felodipine, as an adjuvant to long-term oxygen treatment in COLD patients.
    The European respiratory journal, 1990, Volume: 3, Issue:1

    Topics: Aged; Blood Gas Monitoring, Transcutaneous; Felodipine; Female; Hemodynamics; Humans; Lung Diseases,

1990
Cardiac function and central haemodynamics in severe chronic obstructive lung disease. Acute and long-term effects of felodipine.
    The European respiratory journal, 1988, Volume: 1, Issue:3

    Topics: Aged; Cardiac Output; Felodipine; Female; Heart; Hemodynamics; Humans; Lung Diseases, Obstructive; M

1988
Long-term treatment with a new calcium antagonist, felodipine, in chronic obstructive lung disease.
    European journal of respiratory diseases, 1986, Volume: 68, Issue:5

    Topics: Calcium Channel Blockers; Dose-Response Relationship, Drug; Exercise Test; Felodipine; Humans; Hyper

1986
The effect of a new calcium antagonist, felodipine, on pulmonary hypertension and gas exchange in chronic obstructive lung disease.
    European journal of respiratory diseases, 1985, Volume: 67, Issue:4

    Topics: Adult; Aged; Calcium Channel Blockers; Dose-Response Relationship, Drug; Felodipine; Female; Hemodyn

1985