Page last updated: 2024-10-26

felodipine and Insulin Resistance

felodipine has been researched along with Insulin Resistance in 4 studies

Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.
felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
"Aim of this study was to compare the effect of valsartan and felodipine on blood pressure (BP), plasma leptin (L), insulin sensitivity and plasma norepinephrine (NE) in obese hypertensive patients."9.11Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients. ( Derosa, G; Fogari, E; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A, 2005)
"We examined the effects of ARB administration on hyperinsulinemia-associated capillary density by measuring baseline skin capillary density, capillary density during reactive hyperemia (hyperemic capillary recruitment), and capillary density during venous congestion in 17 hypertensive individuals in the basal state, during a hyperinsulinemic euglycemic clamp, and during a hyperinsulinemic clamp with acute ARB administration (600 mg irbesartan), acute calcium channel blockade (CCB; 10mg felodipine ER), as a control for the reduction in blood pressure, or placebo."5.15Acute angiotensin II receptor blockade improves insulin-induced microvascular function in hypertensive individuals. ( de Leeuw, PW; Houben, AJ; Jonk, AM; Schaper, NC; Serné, EH; Smulders, YM; Stehouwer, CD, 2011)
"Aim of this study was to compare the effect of valsartan and felodipine on blood pressure (BP), plasma leptin (L), insulin sensitivity and plasma norepinephrine (NE) in obese hypertensive patients."5.11Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients. ( Derosa, G; Fogari, E; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seravalle, G1
Brambilla, G1
Pizzalla, DP1
Casati, A1
Riva, M1
Cuspidi, C1
Bombelli, M1
Mancia, G1
Grassi, G1
Jonk, AM1
Houben, AJ1
Schaper, NC1
de Leeuw, PW1
Serné, EH1
Smulders, YM1
Stehouwer, CD1
Fogari, R1
Derosa, G1
Zoppi, A1
Rinaldi, A1
Lazzari, P1
Fogari, E1
Mugellini, A1
Preti, P1
Zhu, X1
Lu, G1
Ou, S1

Trials

4 trials available for felodipine and Insulin Resistance

ArticleYear
Differential effects of enalapril-felodipine versus enalapril-lercanidipine combination drug treatment on sympathetic nerve traffic and metabolic profile in obesity-related hypertension.
    Journal of the American Society of Hypertension : JASH, 2016, Volume: 10, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Monitoring, Ambula

2016
Acute angiotensin II receptor blockade improves insulin-induced microvascular function in hypertensive individuals.
    Microvascular research, 2011, Volume: 82, Issue:1

    Topics: Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel

2011
Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:3

    Topics: Aged; Antihypertensive Agents; Felodipine; Female; Humans; Hypertension; Insulin Resistance; Leptin;

2005
[Effects of plendil on serum oxygen free radicals and insulin resistance in patients with essential hypertension].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 1998, Volume: 19, Issue:1

    Topics: Calcium Channel Blockers; Delayed-Action Preparations; Felodipine; Female; Humans; Hypertension; Ins

1998