felodipine has been researched along with Injury, Myocardial Reperfusion in 7 studies
Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.
felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of the vasoselective calcium antagonist felodipine on myocardial necrosis was studied in 14 anesthetized pigs subjected to 45-min occlusion of the left anterior descending coronary artery (LAD) followed by 24-h reperfusion." | 7.68 | Coronary venous retroinfusion of felodipine reduces myocardial necrosis after coronary occlusion and reperfusion. ( Haga, Y; Hatori, N; Nordlander, M; Rydén, L; Sjöquist, PO, 1993) |
| "The calcium antagonist felodipine, the lipid-peroxidation inhibitor H290/51, and the angiotensin II type 1 (AT1)-receptor antagonist candesartan all exert beneficial effects on myocardial ischemia/reperfusion injury." | 3.70 | Combination of a calcium antagonist, a lipid-peroxidation inhibitor, and an angiotensin AT1-receptor antagonist provides additive myocardial infarct size-limiting effect in pigs. ( Rydén, L; Shimizu, M; Sjöquist, PO; Wang, QD, 1999) |
| " The purpose of this study was to assess the effects of felodipine as a potentially protective agent against myocardial ischemia and reperfusion injury, independent of any negative inotropic actions, when given after the onset of low-flow ischemia." | 3.69 | Beneficial effects of felodipine on myocardial and coronary function during low-flow ischemia and reperfusion. ( Apstein, CS; Bernstein, EA; Eberli, FR; Horowitz, GL; Silverman, AM, 1996) |
| "The effect of the vasoselective calcium antagonist felodipine on myocardial necrosis was studied in 14 anesthetized pigs subjected to 45-min occlusion of the left anterior descending coronary artery (LAD) followed by 24-h reperfusion." | 3.68 | Coronary venous retroinfusion of felodipine reduces myocardial necrosis after coronary occlusion and reperfusion. ( Haga, Y; Hatori, N; Nordlander, M; Rydén, L; Sjöquist, PO, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hatori, N | 1 |
| Haga, Y | 1 |
| Sjöquist, PO | 5 |
| Nordlander, M | 1 |
| Rydén, L | 5 |
| Bernstein, EA | 1 |
| Eberli, FR | 1 |
| Silverman, AM | 1 |
| Horowitz, GL | 1 |
| Apstein, CS | 1 |
| Uriuda, Y | 1 |
| Wang, QD | 4 |
| Li, XS | 1 |
| Nordlander, R | 2 |
| Rose, J | 1 |
| Heusch, G | 1 |
| Shimizu, M | 3 |
7 other studies available for felodipine and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Coronary venous retroinfusion of felodipine reduces myocardial necrosis after coronary occlusion and reperfusion.
Topics: Animals; Coronary Vessels; Felodipine; Female; Hemodynamics; Infusions, Intravenous; Male; Myocardia | 1993 |
Beneficial effects of felodipine on myocardial and coronary function during low-flow ischemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Coronary Circulation; Dose-Response Relat | 1996 |
Coronary venous drug infusion in the ischaemic-reperfused isolated rat heart.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Disease Models, Animal; Felodipine; Heart R | 1996 |
Attenuation of regional myocardial stunning by felodipine.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Disease Models, Animal; Dog | 1996 |
Myocardioprotective effects of felodipine in an antihypertensive dosage: an experimental study in pigs.
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Felodipine; Female; Hemodynamics; Male; | 1998 |
Effects of the angiotensin AT1 receptor blocker candesartan on myocardial ischemic/reperfusion injury.
Topics: Angiotensin Receptor Antagonists; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Calcium | 1999 |
Combination of a calcium antagonist, a lipid-peroxidation inhibitor, and an angiotensin AT1-receptor antagonist provides additive myocardial infarct size-limiting effect in pigs.
Topics: Anesthesia; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Antioxidants; Benzim | 1999 |