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felodipine and Hypertension, Pulmonary

felodipine has been researched along with Hypertension, Pulmonary in 9 studies

Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.
felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
"To explore the effect and the mechanism of felodipine on pulmonary hypertension."7.71[The effect and mechanism of felodipine on monocrotaline induced pulmonary hypertension in rats]. ( Huang, H; Li, X; Zeng, Z, 2002)
"Two women with primary pulmonary hypertension were treated with felodipine, a vasodilating agent."7.67Felodipine in primary pulmonary hypertension. Report of two cases. ( Arnman, K; Rydén, L; Smedgård, P; Thorhallsson, E, 1984)
"In 10 patients with advanced chronic lung disease and pulmonary hypertension central haemodynamics and pulmonary gas exchange were studied at rest and during exercise, before and during continuous infusion of the calcium antagonist felodipine, which lowers vascular resistance by selective action on vascular smooth muscle."7.67The effect of a new calcium antagonist, felodipine, on pulmonary hypertension and gas exchange in chronic obstructive lung disease. ( Bratel, T; Hedenstierna, G; Nyquist, O; Ripe, E, 1985)
"To explore the effect and the mechanism of felodipine on pulmonary hypertension."3.71[The effect and mechanism of felodipine on monocrotaline induced pulmonary hypertension in rats]. ( Huang, H; Li, X; Zeng, Z, 2002)
"The influence of calcium channel antagonists, felodipine and cadmium, as well as pertussis toxin on noradrenaline-induced contractions in pulmonary artery rings from rats with pulmonary hypertension induced by monocrotaline (MCT) were examined."3.69Effects of calcium channel antagonists and pertussis toxin on noradrenaline-induced contractions in pulmonary artery from pulmonary hypertensive rats. ( Lin, BP; MacNicol, BJ; Tabrizchi, R, 1995)
"Two women with primary pulmonary hypertension were treated with felodipine, a vasodilating agent."3.67Felodipine in primary pulmonary hypertension. Report of two cases. ( Arnman, K; Rydén, L; Smedgård, P; Thorhallsson, E, 1984)
"In 10 patients with advanced chronic lung disease and pulmonary hypertension central haemodynamics and pulmonary gas exchange were studied at rest and during exercise, before and during continuous infusion of the calcium antagonist felodipine, which lowers vascular resistance by selective action on vascular smooth muscle."3.67The effect of a new calcium antagonist, felodipine, on pulmonary hypertension and gas exchange in chronic obstructive lung disease. ( Bratel, T; Hedenstierna, G; Nyquist, O; Ripe, E, 1985)
" We have compared the pulmonary vasodilator effects, dose-response characteristics, and tolerability of two calcium channel blockers, amlodipine and extended-release (ER) felodipine, in 10 patients (seven men, age 68+/-4."2.68A comparison of two long-acting vasoselective calcium antagonists in pulmonary hypertension secondary to COPD. ( Alpers, JA; Bune, AJ; Frith, PA; McEvoy, RD; Sajkov, D; Wang, T, 1997)
"Recurrent pulmonary embolism or left-sided pleuropneumonia was suspected."1.29[Splenic infarction caused by paradoxical emboli in severe pulmonary hypertension]. ( Mödl, B; Pfafferott, C; Reuter, N; Wirtzfeld, A, 1996)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's5 (55.56)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zeng, Z1
Huang, H1
Li, X1
Arnman, K1
Rydén, L1
Smedgård, P1
Thorhallsson, E1
Tabrizchi, R1
MacNicol, BJ1
Lin, BP1
Sajkov, D2
McEvoy, RD2
Cowie, RJ1
Bradley, JA1
Antic, R1
Morris, RG1
Frith, PA2
Mödl, B1
Reuter, N1
Pfafferott, C1
Wirtzfeld, A1
Wang, T1
Bune, AJ1
Alpers, JA1
Wanstall, JC1
O'Donnell, SR1
Kay, CS1
Bratel, T2
Hedenstierna, G2
Nyquist, O2
Ripe, E2

Trials

1 trial available for felodipine and Hypertension, Pulmonary

ArticleYear
A comparison of two long-acting vasoselective calcium antagonists in pulmonary hypertension secondary to COPD.
    Chest, 1997, Volume: 111, Issue:6

    Topics: Aged; Amlodipine; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Dose-Re

1997

Other Studies

8 other studies available for felodipine and Hypertension, Pulmonary

ArticleYear
[The effect and mechanism of felodipine on monocrotaline induced pulmonary hypertension in rats].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2002, Volume: 25, Issue:8

    Topics: Animals; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Endothelins; Felodipine; Hyperte

2002
Felodipine in primary pulmonary hypertension. Report of two cases.
    Acta medica Scandinavica, 1984, Volume: 215, Issue:3

    Topics: Adult; Antihypertensive Agents; Felodipine; Female; Hemodynamics; Humans; Hypertension, Pulmonary; N

1984
Effects of calcium channel antagonists and pertussis toxin on noradrenaline-induced contractions in pulmonary artery from pulmonary hypertensive rats.
    Life sciences, 1995, Volume: 56, Issue:14

    Topics: Animals; Aorta; Cadmium; Calcium Channel Blockers; Felodipine; Hypertension, Pulmonary; Male; Monocr

1995
Felodipine improves pulmonary hemodynamics in chronic obstructive pulmonary disease.
    Chest, 1993, Volume: 103, Issue:5

    Topics: Aged; Blood Pressure; Cardiac Output; Echocardiography, Doppler; Felodipine; Female; Humans; Hyperte

1993
[Splenic infarction caused by paradoxical emboli in severe pulmonary hypertension].
    Deutsche medizinische Wochenschrift (1946), 1996, Apr-26, Volume: 121, Issue:17

    Topics: Angiography; Anticoagulants; Calcium Channel Blockers; Diagnosis, Differential; Echocardiography; Fe

1996
Increased relaxation by felodipine on pulmonary artery from rats with monocrotaline-induced pulmonary hypertension does not reflect functional impairment of the endothelium.
    Pulmonary pharmacology, 1991, Volume: 4, Issue:1

    Topics: Animals; Drug Interactions; Endothelins; Endothelium, Vascular; Felodipine; Hypertension, Pulmonary;

1991
Long-term treatment with a new calcium antagonist, felodipine, in chronic obstructive lung disease.
    European journal of respiratory diseases, 1986, Volume: 68, Issue:5

    Topics: Calcium Channel Blockers; Dose-Response Relationship, Drug; Exercise Test; Felodipine; Humans; Hyper

1986
The effect of a new calcium antagonist, felodipine, on pulmonary hypertension and gas exchange in chronic obstructive lung disease.
    European journal of respiratory diseases, 1985, Volume: 67, Issue:4

    Topics: Adult; Aged; Calcium Channel Blockers; Dose-Response Relationship, Drug; Felodipine; Female; Hemodyn

1985