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felodipine and Electrolytes

felodipine has been researched along with Electrolytes in 6 studies

Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.
felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.

Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)

Research Excerpts

ExcerptRelevanceReference
" To study further the interactions between dietary salt intake and antihypertensive drug treatment, we examined the effects of felodipine, a dihydropyridine derivative Ca2+ channel antagonist with natriuretic properties, on blood pressure and the development of left ventricular hypertrophy in the stroke-prone spontaneously hypertensive rats during different levels of sodium chloride in the diet."3.69Cardiovascular effects of felodipine are not antagonized by dietary salt. ( Karppanen, H; Laakso, J; Mervaala, EM, 1994)
" The possibility of an acute pharmacokinetic or pharmacodynamic interaction between the ACE inhibitor ramipril and the calcium antagonist felodipine was examined in 12 normotensive male volunteers."2.67A study of the acute pharmacodynamic interaction of ramipril and felodipine in normotensive subjects. ( Bainbridge, AD; Lees, KR; MacFadyen, RJ; Reid, JL, 1991)
"Felodipine and placebo were infused in a double-blind, crossover study in 10 healthy normotensive volunteers."2.66Haemodynamic, hormonal, and diuretic effects of felodipine in healthy normotensive volunteers. ( Huysmans, FT; Koene, RA; Sluiter, HE; Thien, TA; van Lier, HJ, 1985)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Van Hamersvelt, HW1
Wetzels, JF1
Kloke, HJ1
Koene, RA2
Huysmans, FT2
Mervaala, EM1
Laakso, J1
Karppanen, H1
Lernfelt, B1
Landahl, S1
Johansson, P1
Seligman, L1
Aberg, J1
Bainbridge, AD1
MacFadyen, RJ1
Lees, KR1
Reid, JL1
Sluiter, HE1
Thien, TA1
van Lier, HJ1
Ek, B1
Sjölander, M1
DiBona, GF1
Hallbäck-Nordlander, M1
Ljung, B1

Trials

4 trials available for felodipine and Electrolytes

ArticleYear
Exogenous aldosterone antagonizes distal tubular effects of calcium entry blocker felodipine.
    The American journal of physiology, 1994, Volume: 266, Issue:6 Pt 2

    Topics: Adult; Aldosterone; Calcium Channel Blockers; Diuresis; Electrolytes; Felodipine; Hemodynamics; Huma

1994
Haemodynamic and renal effects of felodipine in young and elderly subjects.
    European journal of clinical pharmacology, 1998, Volume: 54, Issue:8

    Topics: Adult; Age Factors; Aged; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double-Blind

1998
A study of the acute pharmacodynamic interaction of ramipril and felodipine in normotensive subjects.
    British journal of clinical pharmacology, 1991, Volume: 31, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Bridged Bicyclo Compounds; Double-Blind Method; Drug Interaction

1991
Haemodynamic, hormonal, and diuretic effects of felodipine in healthy normotensive volunteers.
    Drugs, 1985, Volume: 29 Suppl 2

    Topics: Adrenocorticotropic Hormone; Adult; Antihypertensive Agents; Blood Pressure; Diuresis; Electrolytes;

1985

Other Studies

2 other studies available for felodipine and Electrolytes

ArticleYear
Cardiovascular effects of felodipine are not antagonized by dietary salt.
    European journal of pharmacology, 1994, Apr-01, Volume: 255, Issue:1-3

    Topics: Animals; Blood Pressure; Cerebrovascular Disorders; Electrolytes; Felodipine; Heart Rate; Hemodynami

1994
Effect of felodipine on renal hemodynamics and excretion in the dog.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 179, Issue:2

    Topics: Animals; Antihypertensive Agents; Dogs; Electrolytes; Felodipine; Glomerular Filtration Rate; Hemody

1985