felodipine has been researched along with Celiac Sprue in 2 studies
Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.
felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A physiologically-based pharmacokinetic (PBPK) population for different severities of CeD was developed." | 5.91 | Physiologically based pharmacokinetic modeling for development and applications of a virtual celiac disease population using felodipine as a model drug. ( Bloomer, J; Mudunuru, J; Nimavardi, A; Salem, F; Taskar, KS; Tompson, D; Turner, DB, 2023) |
| "A phase I, open-label, single-dose, pharmacokinetic study." | 2.94 | Severity of coeliac disease and clinical management study when using a CYP3A4 metabolised medication: a phase I pharmacokinetic study. ( Asher, L; Bailey, DG; Chretien, ML; Dresser, GK; Driman, D; Gregor, J; Parfitt, J, 2020) |
| " A physiologically-based pharmacokinetic (PBPK) population for different severities of CeD was developed." | 1.91 | Physiologically based pharmacokinetic modeling for development and applications of a virtual celiac disease population using felodipine as a model drug. ( Bloomer, J; Mudunuru, J; Nimavardi, A; Salem, F; Taskar, KS; Tompson, D; Turner, DB, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Salem, F | 1 |
| Nimavardi, A | 1 |
| Mudunuru, J | 1 |
| Tompson, D | 1 |
| Bloomer, J | 1 |
| Turner, DB | 1 |
| Taskar, KS | 1 |
| Chretien, ML | 1 |
| Bailey, DG | 1 |
| Asher, L | 1 |
| Parfitt, J | 1 |
| Driman, D | 1 |
| Gregor, J | 1 |
| Dresser, GK | 1 |
1 trial available for felodipine and Celiac Sprue
| Article | Year |
|---|---|
Severity of coeliac disease and clinical management study when using a CYP3A4 metabolised medication: a phase I pharmacokinetic study.
Topics: Adult; Aged; Celiac Disease; Citrus paradisi; Cross-Over Studies; Cytochrome P-450 CYP3A; Dose-Respo | 2020 |
1 other study available for felodipine and Celiac Sprue
| Article | Year |
|---|---|
Physiologically based pharmacokinetic modeling for development and applications of a virtual celiac disease population using felodipine as a model drug.
Topics: Celiac Disease; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Felodi | 2023 |