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felodipine and Alloxan Diabetes

felodipine has been researched along with Alloxan Diabetes in 6 studies

Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.
felodipine : The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.

Research Excerpts

ExcerptRelevanceReference
" In this study we evaluated the effect of global brain ischemia on brain metabolic parameters in normal and diabetic rats treated with a dihydropyridine calcium antagonist, felodipine."3.72The effect of global brain ischemia in normal and diabetic animals: the influence of calcium channel blockers. ( Dunbar, JC; Levy, J; Zhu, Z, 2004)
" Therefore, the present study using thermal pain threshold was taken up to find out, whether felodipine, altered morphine analgesia in experimental diabetes."3.69Felodipine potentiates morphine analgesia in control and streptozotocin diabetic female rats. ( Andrade, C; Chandran, U; Rani, MA; Venkataraman, BV, 1996)
"Felodipine was administered (po) for 4 week to rats with streptozotocin-diabetes of 4 week duration."1.29Effect of felodipine on myocardial function and cholinergic responses in short term streptozotocin diabetes in rats. ( Andrade, C; Jaiprakash, R; Rani, MA; Venkataraman, BV, 1994)
"Enalapril treatment (5 mg/kg/day, n = 11) or felodipine (30 mg/kg/day, n = 11) reduced systolic blood pressure to a comparable degree."1.27Disparate effects of angiotensin converting enzyme inhibitor and calcium blocker treatment on the preservation of renal structure and function following subtotal nephrectomy or streptozotocin-induced diabetes in the rat. ( Cubela, R; Debrevi, L; Jackson, B; Johnston, CI; Whitty, M, 1987)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Levy, J1
Zhu, Z1
Dunbar, JC1
Jaiprakash, R3
Rani, MA4
Venkataraman, BV4
Andrade, C4
Chandran, U1
Jackson, B1
Cubela, R1
Debrevi, L1
Whitty, M1
Johnston, CI1

Other Studies

6 other studies available for felodipine and Alloxan Diabetes

ArticleYear
The effect of global brain ischemia in normal and diabetic animals: the influence of calcium channel blockers.
    Endocrine, 2004, Volume: 25, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain Chemistry; Brain Ischemia; Calcium; Calcium Channel Blockers;

2004
Effect of felodipine on cholinergic responses of the colonic smooth muscle of streptozotocin induced diabetic rats.
    Indian journal of experimental biology, 1995, Volume: 33, Issue:4

    Topics: Acetylcholine; Animals; Colon; Diabetes Mellitus, Experimental; Felodipine; Female; Male; Muscle, Sm

1995
Effect of felodipine on myocardial function and cholinergic responses in short term streptozotocin diabetes in rats.
    Indian journal of experimental biology, 1994, Volume: 32, Issue:9

    Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; Felodipine; Female; Male; Myocardial Contra

1994
Effect of felodipine on serum lipid profile in short term streptozotocin-diabetes in rats.
    Indian journal of experimental biology, 1993, Volume: 31, Issue:3

    Topics: Animals; Cholesterol; Diabetes Mellitus, Experimental; Felodipine; Female; Lipids; Male; Rats; Rats,

1993
Felodipine potentiates morphine analgesia in control and streptozotocin diabetic female rats.
    Indian journal of experimental biology, 1996, Volume: 34, Issue:7

    Topics: Analgesics, Opioid; Animals; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Drug Synergi

1996
Disparate effects of angiotensin converting enzyme inhibitor and calcium blocker treatment on the preservation of renal structure and function following subtotal nephrectomy or streptozotocin-induced diabetes in the rat.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Diabetes Mellitus, Expe

1987