fellutamide-b and Pheochromocytoma

fellutamide-b has been researched along with Pheochromocytoma* in 1 studies

Other Studies

1 other study(ies) available for fellutamide-b and Pheochromocytoma

Article	Year
Neurotrophic peptide aldehydes: solid phase synthesis of fellutamide B and a simplified analog. Bioorganic & medicinal chemistry letters, 2006, Jul-15, Volume: 16, Issue:14 A combination of solid phase and solution phase synthetic methods have been used to complete the total synthesis of the neurotrophic lipopeptide aldehyde fellutamide B (2). The beta-hydroxy aliphatic tail was prepared by regioselective reductive opening of a cyclic sulfate, and later coupled to a solid phase resin. The synthetic compound was then examined in cytotoxicity and nerve growth factor (NGF) induction assays. A simplified analog of fellutamide B also showed activity. Topics: Aldehydes; Amino Acid Sequence; Animals; Cell Line; Cyclization; Dipeptides; Fibroblasts; Humans; Inhibitory Concentration 50; Lipopeptides; Mice; Molecular Sequence Data; Molecular Structure; Neoplasms, Glandular and Epithelial; Nerve Growth Factors; Oligopeptides; Pheochromocytoma; Rats; Sulfates	2006

Article

Year

Neurotrophic peptide aldehydes: solid phase synthesis of fellutamide B and a simplified analog.

Bioorganic & medicinal chemistry letters, 2006, Jul-15, Volume: 16, Issue:14

A combination of solid phase and solution phase synthetic methods have been used to complete the total synthesis of the neurotrophic lipopeptide aldehyde fellutamide B (2). The beta-hydroxy aliphatic tail was prepared by regioselective reductive opening of a cyclic sulfate, and later coupled to a solid phase resin. The synthetic compound was then examined in cytotoxicity and nerve growth factor (NGF) induction assays. A simplified analog of fellutamide B also showed activity.

Topics: Aldehydes; Amino Acid Sequence; Animals; Cell Line; Cyclization; Dipeptides; Fibroblasts; Humans; Inhibitory Concentration 50; Lipopeptides; Mice; Molecular Sequence Data; Molecular Structure; Neoplasms, Glandular and Epithelial; Nerve Growth Factors; Oligopeptides; Pheochromocytoma; Rats; Sulfates

2006