felbamate has been researched along with Syndrome in 10 studies
Felbamate: A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.
felbamate : The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the efficacy of felbamate (FBM) in combination with valproic acid (VPA) in 13 patients with the Lennox-Gastaut syndrome and evaluated the contribution of each drug." | 9.09 | The efficacy of felbamate as add-on therapy to valproic acid in the Lennox-Gastaut syndrome. ( Flamini, R; Gaillard, WD; Kelley, K; Ko, D; Malow, B; Reeves-Tyer, P; Siegel, H; Stertz, B; Theodore, WH, 1999) |
| "Felbamate (FBM, Felbatol/Taloxa), a new antiepileptic drug (AED), was tested in a placebo-controlled add-on design in 73 patients with therapy refractory Lennox-Gastaut syndrome." | 9.07 | Felbamate in the treatment of Lennox-Gastaut syndrome. ( Jensen, PK, 1994) |
| "We studied the efficacy of felbamate in 73 patients ranging in age from 4 to 36 years who had the Lennox-Gastaut syndrome." | 9.07 | Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). ( , 1993) |
| "The behavioral effects of felbamate were assessed in 20 persons, (ages 2 to 19 years) who were participating in a compassionate plea protocol for children with Lennox-Gastaut syndrome." | 7.69 | Behavioral effects of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). ( Coskey, JS; Gay, PE; Mecham, GF; Sadler, T; Thompson, JA, 1995) |
| "We studied the efficacy of felbamate (FBM) in combination with valproic acid (VPA) in 13 patients with the Lennox-Gastaut syndrome and evaluated the contribution of each drug." | 5.09 | The efficacy of felbamate as add-on therapy to valproic acid in the Lennox-Gastaut syndrome. ( Flamini, R; Gaillard, WD; Kelley, K; Ko, D; Malow, B; Reeves-Tyer, P; Siegel, H; Stertz, B; Theodore, WH, 1999) |
| "Felbamate (FBM, Felbatol/Taloxa), a new antiepileptic drug (AED), was tested in a placebo-controlled add-on design in 73 patients with therapy refractory Lennox-Gastaut syndrome." | 5.07 | Felbamate in the treatment of Lennox-Gastaut syndrome. ( Jensen, PK, 1994) |
| "We studied the efficacy of felbamate in 73 patients ranging in age from 4 to 36 years who had the Lennox-Gastaut syndrome." | 5.07 | Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). ( , 1993) |
| "Anticonvulsant hypersensitivity syndrome (AHS) is an uncommon but potentially fatal adverse effect that can occur from exposure to phenytoin, carbamazepine, or phenobarbital." | 4.79 | Anticonvulsant hypersensitivity syndrome. ( Miller, MB; Morkunas, AR, 1997) |
| "The behavioral effects of felbamate were assessed in 20 persons, (ages 2 to 19 years) who were participating in a compassionate plea protocol for children with Lennox-Gastaut syndrome." | 3.69 | Behavioral effects of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). ( Coskey, JS; Gay, PE; Mecham, GF; Sadler, T; Thompson, JA, 1995) |
| "Felbamate was launched in 1993 in the U." | 2.40 | Felbamate: clinical and molecular aspects of a unique antiepileptic drug. ( Aiken, SP; Brown, WM, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (90.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lux, A | 1 |
| Grossmann, R | 1 |
| Maytal, J | 1 |
| Fernando, J | 1 |
| Jensen, PK | 1 |
| Gay, PE | 1 |
| Mecham, GF | 1 |
| Coskey, JS | 1 |
| Sadler, T | 1 |
| Thompson, JA | 1 |
| Morkunas, AR | 1 |
| Miller, MB | 1 |
| Marciani, MG | 1 |
| Spanedda, F | 1 |
| Placidi, F | 1 |
| Bassetti, MA | 1 |
| Romigi, A | 1 |
| Mattia, D | 1 |
| Brown, WM | 1 |
| Aiken, SP | 1 |
| Siegel, H | 1 |
| Kelley, K | 1 |
| Stertz, B | 1 |
| Reeves-Tyer, P | 1 |
| Flamini, R | 1 |
| Malow, B | 1 |
| Gaillard, WD | 1 |
| Ko, D | 1 |
| Theodore, WH | 1 |
2 reviews available for felbamate and Syndrome
| Article | Year |
|---|---|
Anticonvulsant hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Drug Interactions; Felbamate; Humans; Phenoba | 1997 |
Felbamate: clinical and molecular aspects of a unique antiepileptic drug.
Topics: Animals; Anticonvulsants; Clinical Trials as Topic; Drug Resistance; Epilepsy; Felbamate; Humans; In | 1998 |
3 trials available for felbamate and Syndrome
| Article | Year |
|---|---|
Felbamate in the treatment of Lennox-Gastaut syndrome.
Topics: Adult; Anticonvulsants; Child; Drugs, Investigational; Epilepsies, Partial; Epilepsy; Felbamate; Fol | 1994 |
Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome).
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Doubl | 1993 |
The efficacy of felbamate as add-on therapy to valproic acid in the Lennox-Gastaut syndrome.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cross-Over Studies; Double-Blind Method; Drug | 1999 |
5 other studies available for felbamate and Syndrome
| Article | Year |
|---|---|
The effectiveness of felbamate for drug-resistant infantile spasms.
Topics: Anticonvulsants; Felbamate; Humans; Spasms, Infantile; Syndrome | 2020 |
Rectal administration of felbamate in a child with Lennox-Gastaut syndrome.
Topics: Administration, Rectal; Anticonvulsants; Child, Preschool; Epilepsy; Felbamate; Hemiplegia; Humans; | 1994 |
Felbamate.
Topics: Adult; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Drug Interactions; Felbamate; Huma | 1993 |
Behavioral effects of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome).
Topics: Adolescent; Anticonvulsants; Brain Damage, Chronic; Child; Child Behavior Disorders; Child, Preschoo | 1995 |
Changes of the EEG paroxysmal pattern during felbamate therapy in Lennox-Gastaut syndrome: a case report.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Drug Therapy, | 1998 |