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felbamate and Syndrome

felbamate has been researched along with Syndrome in 10 studies

Felbamate: A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.
felbamate : The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"We studied the efficacy of felbamate (FBM) in combination with valproic acid (VPA) in 13 patients with the Lennox-Gastaut syndrome and evaluated the contribution of each drug."9.09The efficacy of felbamate as add-on therapy to valproic acid in the Lennox-Gastaut syndrome. ( Flamini, R; Gaillard, WD; Kelley, K; Ko, D; Malow, B; Reeves-Tyer, P; Siegel, H; Stertz, B; Theodore, WH, 1999)
"Felbamate (FBM, Felbatol/Taloxa), a new antiepileptic drug (AED), was tested in a placebo-controlled add-on design in 73 patients with therapy refractory Lennox-Gastaut syndrome."9.07Felbamate in the treatment of Lennox-Gastaut syndrome. ( Jensen, PK, 1994)
"We studied the efficacy of felbamate in 73 patients ranging in age from 4 to 36 years who had the Lennox-Gastaut syndrome."9.07Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). ( , 1993)
"The behavioral effects of felbamate were assessed in 20 persons, (ages 2 to 19 years) who were participating in a compassionate plea protocol for children with Lennox-Gastaut syndrome."7.69Behavioral effects of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). ( Coskey, JS; Gay, PE; Mecham, GF; Sadler, T; Thompson, JA, 1995)
"We studied the efficacy of felbamate (FBM) in combination with valproic acid (VPA) in 13 patients with the Lennox-Gastaut syndrome and evaluated the contribution of each drug."5.09The efficacy of felbamate as add-on therapy to valproic acid in the Lennox-Gastaut syndrome. ( Flamini, R; Gaillard, WD; Kelley, K; Ko, D; Malow, B; Reeves-Tyer, P; Siegel, H; Stertz, B; Theodore, WH, 1999)
"Felbamate (FBM, Felbatol/Taloxa), a new antiepileptic drug (AED), was tested in a placebo-controlled add-on design in 73 patients with therapy refractory Lennox-Gastaut syndrome."5.07Felbamate in the treatment of Lennox-Gastaut syndrome. ( Jensen, PK, 1994)
"We studied the efficacy of felbamate in 73 patients ranging in age from 4 to 36 years who had the Lennox-Gastaut syndrome."5.07Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). ( , 1993)
"Anticonvulsant hypersensitivity syndrome (AHS) is an uncommon but potentially fatal adverse effect that can occur from exposure to phenytoin, carbamazepine, or phenobarbital."4.79Anticonvulsant hypersensitivity syndrome. ( Miller, MB; Morkunas, AR, 1997)
"The behavioral effects of felbamate were assessed in 20 persons, (ages 2 to 19 years) who were participating in a compassionate plea protocol for children with Lennox-Gastaut syndrome."3.69Behavioral effects of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). ( Coskey, JS; Gay, PE; Mecham, GF; Sadler, T; Thompson, JA, 1995)
"Felbamate was launched in 1993 in the U."2.40Felbamate: clinical and molecular aspects of a unique antiepileptic drug. ( Aiken, SP; Brown, WM, 1998)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (90.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Lux, A1
Grossmann, R1
Maytal, J1
Fernando, J1
Jensen, PK1
Gay, PE1
Mecham, GF1
Coskey, JS1
Sadler, T1
Thompson, JA1
Morkunas, AR1
Miller, MB1
Marciani, MG1
Spanedda, F1
Placidi, F1
Bassetti, MA1
Romigi, A1
Mattia, D1
Brown, WM1
Aiken, SP1
Siegel, H1
Kelley, K1
Stertz, B1
Reeves-Tyer, P1
Flamini, R1
Malow, B1
Gaillard, WD1
Ko, D1
Theodore, WH1

Reviews

2 reviews available for felbamate and Syndrome

ArticleYear
Anticonvulsant hypersensitivity syndrome.
    Critical care clinics, 1997, Volume: 13, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Drug Interactions; Felbamate; Humans; Phenoba

1997
Felbamate: clinical and molecular aspects of a unique antiepileptic drug.
    Critical reviews in neurobiology, 1998, Volume: 12, Issue:3

    Topics: Animals; Anticonvulsants; Clinical Trials as Topic; Drug Resistance; Epilepsy; Felbamate; Humans; In

1998

Trials

3 trials available for felbamate and Syndrome

ArticleYear
Felbamate in the treatment of Lennox-Gastaut syndrome.
    Epilepsia, 1994, Volume: 35 Suppl 5

    Topics: Adult; Anticonvulsants; Child; Drugs, Investigational; Epilepsies, Partial; Epilepsy; Felbamate; Fol

1994
Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome).
    The New England journal of medicine, 1993, 01-07, Volume: 328, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Doubl

1993
The efficacy of felbamate as add-on therapy to valproic acid in the Lennox-Gastaut syndrome.
    Epilepsy research, 1999, Volume: 34, Issue:2-3

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cross-Over Studies; Double-Blind Method; Drug

1999

Other Studies

5 other studies available for felbamate and Syndrome

ArticleYear
The effectiveness of felbamate for drug-resistant infantile spasms.
    Developmental medicine and child neurology, 2020, Volume: 62, Issue:5

    Topics: Anticonvulsants; Felbamate; Humans; Spasms, Infantile; Syndrome

2020
Rectal administration of felbamate in a child with Lennox-Gastaut syndrome.
    Neurology, 1994, Volume: 44, Issue:10

    Topics: Administration, Rectal; Anticonvulsants; Child, Preschool; Epilepsy; Felbamate; Hemiplegia; Humans;

1994
Felbamate.
    The Medical letter on drugs and therapeutics, 1993, Nov-26, Volume: 35, Issue:910

    Topics: Adult; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Drug Interactions; Felbamate; Huma

1993
Behavioral effects of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome).
    Psychological reports, 1995, Volume: 77, Issue:3 Pt 2

    Topics: Adolescent; Anticonvulsants; Brain Damage, Chronic; Child; Child Behavior Disorders; Child, Preschoo

1995
Changes of the EEG paroxysmal pattern during felbamate therapy in Lennox-Gastaut syndrome: a case report.
    The International journal of neuroscience, 1998, Volume: 95, Issue:3-4

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Drug Therapy,

1998