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felbamate and Subarachnoid Hemorrhage

felbamate has been researched along with Subarachnoid Hemorrhage in 1 studies

Felbamate: A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.
felbamate : The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.

Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.

Research Excerpts

ExcerptRelevanceReference
" The aim of this dose-response study was to evaluate the effect of FBM after experimental SAH in rats on (1) behavioral deficits (employing a battery of assessment tasks days 1-5 post-injury) and (2) blood-brain barrier (BBB) permeability changes (quantifying microvascular alterations according to the extravasation of protein-bound Evans Blue by a spectrophotofluorimetric technique 2 days post-injury)."5.34NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat. ( Angileri, FF; Arcadi, F; Bramanti, P; Caffo, M; Caruso, G; Costa, C; Germanò, A; Hayes, RL; Lewis, SB; Meli, F; Newcomb-Fernandez, J; Pineda, JA; Wang, KK, 2007)
" The aim of this dose-response study was to evaluate the effect of FBM after experimental SAH in rats on (1) behavioral deficits (employing a battery of assessment tasks days 1-5 post-injury) and (2) blood-brain barrier (BBB) permeability changes (quantifying microvascular alterations according to the extravasation of protein-bound Evans Blue by a spectrophotofluorimetric technique 2 days post-injury)."1.34NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat. ( Angileri, FF; Arcadi, F; Bramanti, P; Caffo, M; Caruso, G; Costa, C; Germanò, A; Hayes, RL; Lewis, SB; Meli, F; Newcomb-Fernandez, J; Pineda, JA; Wang, KK, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Germanò, A1
Caffo, M1
Angileri, FF1
Arcadi, F1
Newcomb-Fernandez, J1
Caruso, G1
Meli, F1
Pineda, JA1
Lewis, SB1
Wang, KK1
Bramanti, P1
Costa, C1
Hayes, RL1

Other Studies

1 other study available for felbamate and Subarachnoid Hemorrhage

ArticleYear
NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat.
    Journal of neurotrauma, 2007, Volume: 24, Issue:4

    Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Body Weight; Cerebrovascular Circulation; Dose-Respo

2007