felbamate has been researched along with Spasms, Infantile in 8 studies
Felbamate: A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.
felbamate : The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.
Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The mainstay of treatment is with multiple anti-seizure medications (ASMs); however, the ASMs themselves can be associated with psychobehavioural adverse events, and effects (negative or positive) on cognition and sleep." | 2.82 | Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies. ( Schubert-Bast, S; Strzelczyk, A, 2022) |
| "Felbamate was initiated at a mean age of 13." | 1.56 | Felbamate for infantile spasms syndrome resistant to first-line treatments. ( Auvin, S; Bellavoine, V; Delanoe, C; Dozières-Puyravel, B; Ilea, A; Nasser, H, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strzelczyk, A | 1 |
| Schubert-Bast, S | 1 |
| Dozières-Puyravel, B | 1 |
| Nasser, H | 1 |
| Bellavoine, V | 1 |
| Ilea, A | 1 |
| Delanoe, C | 1 |
| Auvin, S | 1 |
| Lux, A | 1 |
| Hussain, SA | 1 |
| Asilnejad, B | 1 |
| Heesch, J | 1 |
| Navarro, M | 1 |
| Ji, M | 1 |
| Shrey, DW | 1 |
| Rajaraman, RR | 1 |
| Sankar, R | 1 |
| Hurst, DL | 1 |
| Rolan, TD | 1 |
| Stafstrom, CE | 1 |
| Hosain, S | 1 |
| Nagarajan, L | 1 |
| Carson, D | 1 |
| Solomon, G | 1 |
| Mast, J | 1 |
| Labar, D | 1 |
| Pellock, JM | 1 |
| Appleton, R | 1 |
2 reviews available for felbamate and Spasms, Infantile
| Article | Year |
|---|---|
Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies.
Topics: Autism Spectrum Disorder; Bromides; Cannabidiol; Clobazam; Cognition; Ethosuximide; Everolimus; Felb | 2022 |
Use of new antiepileptic drugs in the treatment of childhood epilepsy.
Topics: Acetates; Adult; Age Factors; Amines; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanec | 1999 |
6 other studies available for felbamate and Spasms, Infantile
| Article | Year |
|---|---|
Felbamate for infantile spasms syndrome resistant to first-line treatments.
Topics: Anticonvulsants; Drug Resistance; Electroencephalography; Felbamate; Female; Humans; Infant; Male; R | 2020 |
The effectiveness of felbamate for drug-resistant infantile spasms.
Topics: Anticonvulsants; Felbamate; Humans; Spasms, Infantile; Syndrome | 2020 |
Felbamate in the treatment of refractory epileptic spasms.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Felbamate; Female; Humans; Infant; M | 2020 |
The use of felbamate to treat infantile spasms.
Topics: Anticonvulsants; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Elec | 1995 |
The use of felbamate to treat infantile spasms.
Topics: Anticonvulsants; Felbamate; Female; Humans; Infant; Male; Phenylcarbamates; Propylene Glycols; Spasm | 1996 |
Felbamate for refractory infantile spasms.
Topics: Anticonvulsants; Electroencephalography; Felbamate; Female; Humans; Infant; Infant, Newborn; Male; P | 1997 |