felbamate has been researched along with Necrosis in 2 studies
Felbamate: A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.
felbamate : The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The neuroprotective effects of felbamate were tested in a model of incomplete cerebral ischemia and hypoxia in 7-day-old rat pups." | 3.68 | Felbamate reduces hypoxic-ischemic brain damage in vivo. ( Adams, LM; Hattori, H; Schwartz, PH; Wasterlain, CG, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Neil, MG | 1 |
| Perdun, CS | 1 |
| Wilson, MB | 1 |
| McGown, ST | 1 |
| Patel, S | 1 |
| Wasterlain, CG | 1 |
| Adams, LM | 1 |
| Hattori, H | 1 |
| Schwartz, PH | 1 |
2 other studies available for felbamate and Necrosis
| Article | Year |
|---|---|
Felbamate-associated fatal acute hepatic necrosis.
Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Epilepsy, Tonic-Clonic; Fatal Outcome; Felb | 1996 |
Felbamate reduces hypoxic-ischemic brain damage in vivo.
Topics: Animals; Anticonvulsants; Behavior, Animal; Body Temperature; Brain Ischemia; Felbamate; Female; Hip | 1992 |