felbamate has been researched along with Convulsive Generalized Seizure Disorder in 10 studies
Felbamate: A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.
felbamate : The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the efficacy of felbamate in 73 patients ranging in age from 4 to 36 years who had the Lennox-Gastaut syndrome." | 9.07 | Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). ( , 1993) |
| "We studied the efficacy of felbamate in 73 patients ranging in age from 4 to 36 years who had the Lennox-Gastaut syndrome." | 5.07 | Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). ( , 1993) |
| "Felbamate (FBM) is a new antiepileptic drug (AED) that has been evaluated in partial seizures and in the Lennox-Gastaut syndrome (LGS)." | 2.67 | Felbamate in the treatment of Lennox-Gastaut syndrome: results of a 12-month open-label study following a randomized clinical trial. ( Dodson, WE, 1993) |
| "Felbamate (FBM) is a new antiepileptic drug (AED) that has been tested in open and controlled studies in patients with therapy-refractory partial-onset seizures." | 2.67 | Felbamate in the treatment of refractory partial-onset seizures. ( Jensen, PK, 1993) |
| "Anorexia and insomnia were reported in 20% and 16% of the patients, respectively." | 1.29 | Efficacy of felbamate in therapy for partial epilepsy in children. ( Anderson, J; Carmant, L; Holmes, GL; Mikati, MA; Rifai, N; Sawyer, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (80.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodie, MJ | 1 |
| Pellock, JM | 1 |
| Luer, MS | 1 |
| Carmant, L | 1 |
| Holmes, GL | 1 |
| Sawyer, S | 1 |
| Rifai, N | 1 |
| Anderson, J | 1 |
| Mikati, MA | 1 |
| Dodson, WE | 1 |
| Jensen, PK | 1 |
| Snodgrass, SR | 1 |
| Bourgeois, B | 1 |
| Benbadis, SR | 1 |
| Kmieć, T | 1 |
| Jóźwiak, S | 1 |
| Kuczyński, D | 1 |
| Karkowska, B | 1 |
| Bachański, M | 1 |
1 review available for felbamate and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Clinical use of drugs useful in the treatment of atonic seizures.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Epilepsy, Genera | 1995 |
4 trials available for felbamate and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Felbamate in the treatment of Lennox-Gastaut syndrome: results of a 12-month open-label study following a randomized clinical trial.
Topics: Anticonvulsants; Child; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalograph | 1993 |
Felbamate in the treatment of refractory partial-onset seizures.
Topics: Adult; Anticonvulsants; Child; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; | 1993 |
Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome).
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Doubl | 1993 |
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combi | 2000 |
5 other studies available for felbamate and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Taming the brain storms: felbamate updated.
Topics: Anemia, Aplastic; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Approval; Drug Monit | 1995 |
Criteria for use of felbamate in adult, adolescent, and child inpatients and outpatients.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsies, Parti | 1994 |
Efficacy of felbamate in therapy for partial epilepsy in children.
Topics: Adolescent; Age Factors; Anorexia; Anticonvulsants; Child; Child, Preschool; Drug Combinations; Drug | 1994 |
Felbamate therapy in the Lennox-Gastaut syndrome.
Topics: Anticonvulsants; Epilepsy, Generalized; Felbamate; Humans; Phenylcarbamates; Propylene Glycols; Seiz | 1993 |
Practice advisory.
Topics: Abstracting and Indexing; Anticonvulsants; Epilepsy, Generalized; Felbamate; Humans; Peer Review; Pe | 2000 |