felbamate has been researched along with Chronic Kidney Failure in 2 studies
Felbamate: A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.
felbamate : The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since 1993, eight new antiepileptic drugs (AEDs) have become available in the United States for the treatment of epilepsy: felbamate, gabapentin, lamotrigine, topiramate, tiagabine, levetiracetam, oxcarbazepine, and zonisamide." | 4.81 | Some common issues in the use of antiepileptic drugs. ( Asconapé, JJ, 2002) |
| "Compared with controls, apparent total body clearance, renal clearance and urinary excretion of felbamate were decreased, and half-life, Cmax and AUC values were increased in subjects with renal dysfunction." | 1.30 | Single-dose pharmacokinetics of felbamate in patients with renal dysfunction. ( Affrime, MB; Banfield, C; Colucci, R; Glue, P; Lin, C; Pai, S; Sulowicz, W, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asconapé, JJ | 1 |
| Glue, P | 1 |
| Sulowicz, W | 1 |
| Colucci, R | 1 |
| Banfield, C | 1 |
| Pai, S | 1 |
| Lin, C | 1 |
| Affrime, MB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Normalization of Sodium on Bone Markers in Patients With Epilepsy. A Randomized Single-blinded Placebo-controlled Trial.[NCT03371199] | 21 participants (Actual) | Interventional | 2017-12-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for felbamate and Chronic Kidney Failure
| Article | Year |
|---|---|
Some common issues in the use of antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Anticonvulsants; Body Weight; Cognition Disorders; Drug E | 2002 |
1 other study available for felbamate and Chronic Kidney Failure
| Article | Year |
|---|---|
Single-dose pharmacokinetics of felbamate in patients with renal dysfunction.
Topics: Adult; Anticonvulsants; Felbamate; Humans; Kidney Failure, Chronic; Male; Middle Aged; Phenylcarbama | 1997 |