felbamate has been researched along with Anorexia in 5 studies
Felbamate: A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.
felbamate : The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.
Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The usefulness of felbamate (FBM) levels in managing epilepsy patients has not been determined." | 7.69 | Felbamate levels in patients with epilepsy. ( Harden, CL; Kutt, H; Trifiletti, R, 1996) |
| "Felbamate (FBM) pharmacokinetic parameters, safety and tolerability in the dose range of 1,200-6,000 mg/day were assessed in two open-label studies with similar designs." | 6.68 | Tolerability and pharmacokinetics of monotherapy felbamate doses of 1,200-6,000 mg/day in subjects with epilepsy. ( Lyness, WH; Narang-Sachdeo, SK; Perhach, JL; Rosenberg, A; Sachdeo, R; Shumaker, RC, 1997) |
| " By univariate analysis, those achieving seizure remission were probably much older, to have a shorter history of epilepsy and a lower frequency of seizures before felbamate therapy." | 3.74 | Efficacy and safety of felbamate in children under 4 years of age: a retrospective chart review. ( Balestri, P; Berardi, R; Coppola, G; Cordelli, DM; Franzoni, E; Grosso, S; Verrotti, A, 2008) |
| "The usefulness of felbamate (FBM) levels in managing epilepsy patients has not been determined." | 3.69 | Felbamate levels in patients with epilepsy. ( Harden, CL; Kutt, H; Trifiletti, R, 1996) |
| "Felbamate (FBM) pharmacokinetic parameters, safety and tolerability in the dose range of 1,200-6,000 mg/day were assessed in two open-label studies with similar designs." | 2.68 | Tolerability and pharmacokinetics of monotherapy felbamate doses of 1,200-6,000 mg/day in subjects with epilepsy. ( Lyness, WH; Narang-Sachdeo, SK; Perhach, JL; Rosenberg, A; Sachdeo, R; Shumaker, RC, 1997) |
| "Felbamate (FBM) was the first of the new antiepileptic drugs (AEDs) approved in the United States in 1993 with broad-spectrum efficacy against partial and generalized seizures of various types, and indicated for use as adjunctive and monotherapy." | 2.40 | Felbamate. ( Pellock, JM, 1999) |
| "Anorexia and insomnia were reported in 20% and 16% of the patients, respectively." | 1.29 | Efficacy of felbamate in therapy for partial epilepsy in children. ( Anderson, J; Carmant, L; Holmes, GL; Mikati, MA; Rifai, N; Sawyer, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grosso, S | 1 |
| Cordelli, DM | 1 |
| Coppola, G | 1 |
| Franzoni, E | 1 |
| Verrotti, A | 1 |
| Berardi, R | 1 |
| Balestri, P | 1 |
| Carmant, L | 1 |
| Holmes, GL | 1 |
| Sawyer, S | 1 |
| Rifai, N | 1 |
| Anderson, J | 1 |
| Mikati, MA | 1 |
| Harden, CL | 1 |
| Trifiletti, R | 1 |
| Kutt, H | 1 |
| Sachdeo, R | 1 |
| Narang-Sachdeo, SK | 1 |
| Shumaker, RC | 1 |
| Perhach, JL | 1 |
| Lyness, WH | 1 |
| Rosenberg, A | 1 |
| Pellock, JM | 1 |
1 review available for felbamate and Anorexia
| Article | Year |
|---|---|
Felbamate.
Topics: Adult; Age Factors; Anemia, Aplastic; Anorexia; Anticonvulsants; Child; Drug Administration Schedule | 1999 |
1 trial available for felbamate and Anorexia
| Article | Year |
|---|---|
Tolerability and pharmacokinetics of monotherapy felbamate doses of 1,200-6,000 mg/day in subjects with epilepsy.
Topics: Adolescent; Adult; Anorexia; Anticonvulsants; Area Under Curve; Dose-Response Relationship, Drug; Dr | 1997 |
3 other studies available for felbamate and Anorexia
| Article | Year |
|---|---|
Efficacy and safety of felbamate in children under 4 years of age: a retrospective chart review.
Topics: Anorexia; Anticonvulsants; Child, Preschool; Drug Evaluation; Drug Resistance; Epilepsy; Felbamate; | 2008 |
Efficacy of felbamate in therapy for partial epilepsy in children.
Topics: Adolescent; Age Factors; Anorexia; Anticonvulsants; Child; Child, Preschool; Drug Combinations; Drug | 1994 |
Felbamate levels in patients with epilepsy.
Topics: Adolescent; Anorexia; Anticonvulsants; Child; Child, Preschool; Chromatography, High Pressure Liquid | 1996 |