Page last updated: 2024-10-26

felbamate and Aging

felbamate has been researched along with Aging in 3 studies

Felbamate: A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.
felbamate : The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" These findings suggest that felbamate dosing should be relatively uncomplicated in children relative to that in adults."2.68The effect of age on the apparent clearance of felbamate: a retrospective analysis using nonlinear mixed-effects modeling. ( Affrime, MB; Banfield, CR; Glue, P; Jen, JF; Jensen, PK; Perhach, JL; Schumaker, RC; Zhu, GR, 1996)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacala, A1
Adusumalli, VE1
Kucharczyk, N1
Sofia, RD1
Banfield, CR1
Zhu, GR1
Jen, JF1
Jensen, PK1
Schumaker, RC1
Perhach, JL1
Affrime, MB1
Glue, P1
Haugvicová, R1
Kubová, H1
Mares, P1

Trials

1 trial available for felbamate and Aging

ArticleYear
The effect of age on the apparent clearance of felbamate: a retrospective analysis using nonlinear mixed-effects modeling.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Anticonvulsants; Bayes Theorem; Body Weight; Child; Child, Preschool

1996

Other Studies

2 other studies available for felbamate and Aging

ArticleYear
Determination of the anticonvulsant felbamate and its three metabolites in brain and heart tissue of rats.
    Journal of chromatography, 1993, May-05, Volume: 614, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Anticonvulsants; Brain Chemistry; Chromatography, High Pressure Li

1993
Qualitative changes of anticonvulsant action of felbamate during development in rats.
    Brain & development, 1998, Volume: 20, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Fe

1998