Page last updated: 2024-09-04

febuxostat and Renal Insufficiency

febuxostat has been researched along with Renal Insufficiency in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Chen, J; Hu, Y; Jiang, B; Lou, H; Ruan, Z; Xu, Y; Yang, D1
Arai, H; Ishimaru, Y; Kitamura, M; Maeda, K; Matsumura, K; Mori, T; Nishino, T; Obata, Y; Sohara, E; Uchida, S; Umene, R; Uramatsu, T1
Becker, MA; Hunt, BJ; Jackson, RL; MacDonald, PA1
Araki, H; Chisaki, Y; Hira, D; Maegawa, H; Morita, SY; Noda, S; Terada, T; Uzu, T; Yano, Y1
Carcedo, D; Díaz-Torné, C; Perez-Ruiz, F1
Becker, MA; Gunawardhana, L; Hunt, B; MacDonald, P; Saag, KG; Whelton, A1
Hayashi, T; Hiramitsu, S; Hisatome, I; Jinnouchi, H; Kakuda, H; Kawai, N; Kimura, K; Kojima, S; Matsui, K; Mori, H; Ogawa, H; Ohya, Y; Saito, Y; Sugawara, M; Tokutake, E; Uchiyama, K; Wakasa, Y; Waki, M; Yokota, N1
Hosoya, T; Iwao, O; Ohno, I; Tatsuo, H1
Hoshide, S; Hosoya, T; Ishikawa, T; Komoriya, K; Kubo, J; Ohno, I; Takahashi, Y; Tsuchimoto, M1

Trials

6 trial(s) available for febuxostat and Renal Insufficiency

ArticleYear
Diabetes and gout: efficacy and safety of febuxostat and allopurinol.
    Diabetes, obesity & metabolism, 2013, Volume: 15, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Body Mass Index; Cohort Studies; Comorbidity; Diabetes Complications; Dose-Response Relationship, Drug; Enzyme Inhibitors; Febuxostat; Female; Gout; Gout Suppressants; Humans; Intention to Treat Analysis; Kidney; Lost to Follow-Up; Male; Middle Aged; Obesity; Patient Dropouts; Renal Insufficiency; Thiazoles; Xanthine Oxidase; Young Adult

2013
Population Pharmacokinetics and Therapeutic Efficacy of Febuxostat in Patients with Severe Renal Impairment.
    Pharmacology, 2015, Volume: 96, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Febuxostat; Female; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Renal Insufficiency; Retrospective Studies

2015
Impact of Febuxostat on Renal Function in Gout Patients With Moderate-to-Severe Renal Impairment.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Febuxostat; Female; Glomerular Filtration Rate; Gout; Gout Suppressants; Humans; Male; Middle Aged; Prospective Studies; Renal Insufficiency; Severity of Illness Index

2016
Rationale, design, and baseline characteristics of a study to evaluate the effect of febuxostat in preventing cerebral, cardiovascular, and renal events in patients with hyperuricemia.
    Journal of cardiology, 2017, Volume: 69, Issue:1

    Topics: Aged; Aged, 80 and over; Brain Diseases; Cardiovascular Diseases; Cause of Death; Febuxostat; Female; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Prospective Studies; Renal Insufficiency; Research Design; Single-Blind Method; Treatment Outcome; Uric Acid

2017
A repeated oral administration study of febuxostat (TMX-67), a non-purine-selective inhibitor of xanthine oxidase, in patients with impaired renal function in Japan: pharmacokinetic and pharmacodynamic study.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:4 Suppl 2

    Topics: Administration, Oral; Adult; Aged; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Febuxostat; Female; Follow-Up Studies; Glomerular Filtration Rate; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Oxypurinol; Renal Insufficiency; Thiazoles; Treatment Outcome; Uric Acid; Xanthine Oxidase; Young Adult

2011
PK/PD and safety of a single dose of TMX-67 (febuxostat) in subjects with mild and moderate renal impairment.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Area Under Curve; Enzyme Inhibitors; Febuxostat; Female; Humans; Kidney; Kidney Diseases; Male; Renal Insufficiency; Thiazoles; Time Factors; Xanthine Oxidase

2004

Other Studies

3 other study(ies) available for febuxostat and Renal Insufficiency

ArticleYear
Simulation of febuxostat pharmacokinetics in healthy subjects and patients with impaired kidney function using physiologically based pharmacokinetic modeling.
    Biopharmaceutics & drug disposition, 2022, Volume: 43, Issue:4

    Topics: Febuxostat; Gout; Gout Suppressants; Healthy Volunteers; Humans; Kidney; Renal Insufficiency

2022
Bartter syndrome representing digenic-based salt-losing tubulopathies presumably accelerated by renal insufficiency.
    CEN case reports, 2020, Volume: 9, Issue:4

    Topics: Adult; Bartter Syndrome; Chloride Channels; Diagnosis, Differential; Drug Therapy, Combination; Febuxostat; Female; Gitelman Syndrome; Gout Suppressants; Heterozygote; Humans; Hyperuricemia; Hypokalemia; Mutation; Phenotype; Potassium Chloride; Renal Insufficiency; Solute Carrier Family 12, Member 1; Treatment Outcome

2020
Cost-effectiveness analysis of febuxostat in patients with gout in Spain.
    Journal of medical economics, 2016, Volume: 19, Issue:6

    Topics: Allopurinol; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Markov Chains; Models, Econometric; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Renal Insufficiency; Spain

2016