febuxostat has been researched along with Blood Pressure, High in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 17 (60.71) | 24.3611 |
| 2020's | 11 (39.29) | 2.80 |
| Authors | Studies |
|---|---|
| Ito, O; Kohzuki, M; Miura, T; Namai-Takahashi, A; Ogawa, Y; Qiu, J; Sakuyama, A; Xu, L | 1 |
| Allada, R; Ann, EYC; Ganesan, T; Ghosal, S; Kwok, J; Muthudoss, P; Omar, MF; See, HH; Shahnawaz, SS; Voguri, RS | 1 |
| Arima, H; Funakoshi, R; Iseki, K; Ishida, A; Kinjyo, K; Kochi, M; Kohagura, K; Nakamura, T; Ohya, Y; Sakima, A; Satoh, A; Tana, T; Yamazato, M; Zamami, R | 1 |
| Cheung, PP; Chua, CKT; Lim, AYN; Santosa, A; Teng, GG | 1 |
| Hoshide, S; Kabutoya, T; Kario, K; Ueno, H | 1 |
| Hirose, T; Ito, O; Kohzuki, M; Mori, T; Nakamura, T; Ohsaki, Y; Rong, R; Takahashi, K; Totsune, K; Yamakoshi, S | 1 |
| Gu, J; Lin, H; Pan, JA; Wang, CQ; Zhang, JF | 1 |
| Chen, Q; Fan, S; Gao, Y; Hu, H; Shi, X; Wang, P; Yao, J | 1 |
| Barrientos-Regala, M; Castillo, RR; Macabeo, RA; Pestaño, NS; Punzalan, FER; Ramirez-Ragasa, R; Tumanan-Mendoza, B | 1 |
| Abe, Y; Fukumoto, Y; Hisatome, I; Hongou, M; Hoshide, S; Kario, K; Kasai, T; Kiuchi, M; Kiyosue, A; Kuga, H; Kuramochi, J; Miyazaki, S; Nishizawa, M; Ohtani, H; Tomita, F; Yasu, T | 1 |
| Aonuma, K; Duo, F; Ieda, M; Li, S; Mori, H; Murakata, Y; Murakoshi, N; Nogami, A; Okabe, Y; Sato, A; Shimoda, Y; Song, Z; Tajiri, K; Xu, D; Yuan, Z | 1 |
| Borghi, C; Bove, M; Cicero, AFG | 1 |
| Feig, DI; Gunawardhana, L; Hunt, B; McLean, L; Palmer, RN; Punzi, HA; Whelton, A | 1 |
| Balia, F; Borrelli, S; De Nicola, L; De Stefano, T; Garofalo, C; Minutolo, R; Nettuno, F; Pacilio, M; Sagliocchi, A; Scarpati, L; Sguazzo, A; Vinci, G; Vita, C | 1 |
| Treviño-Becerra, A | 1 |
| Becker, MA; Castillo, M; Gunawardhana, L; Hunt, B; Kisfalvi, K; Saag, KG; Whelton, A | 1 |
| Chuma, M; Fujino, H; Fukushima, K; Goda, M; Horinouchi, Y; Ikeda, Y; Ikuto, R; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kondo, M; Murai, Y; Takechi, K; Tsuchiya, K; Zamami, Y | 1 |
| Cicalese, S; Eguchi, S; Scalia, R | 1 |
| Kang, EH; Kim, SC | 1 |
| Ohno, I | 1 |
| Joo, H; Joo, K; Jung, KH; Kwon, SR; Lim, MJ; Park, W | 1 |
| Hirayama, A; Nagao, K; Tani, S | 1 |
| Higa, A; Iseki, K; Ishida, A; Kohagura, K; Nagahama, K; Ohya, Y; Sakima, A; Tana, T; Yamazato, M | 1 |
| Kobayashi, T; Masuzaki, H; Matsui, C; Nomura, J; Shirakura, T; Tamura, M | 1 |
| Arima, H; Hayashi, S; Ishizuka, A; Iwashima, Y; Kawano, Y; Kishida, M; Nakamura, S; Ohta, Y; Yoshihara, F | 1 |
| Aviña-Zubieta, JA; Choi, HK; De Vera, MA; McCormick, N; Rai, SK; Sayre, EC; Shojania, K | 1 |
| Becker, MA; Espinoza, LR; Lademacher, C; Lloyd, E; MacDonald, P; Schumacher, HR; Wells, AF | 1 |
| Burnett, RJ; Davis, RP; Fink, GD; Garver, HS; Szasz, T; Watts, SW | 1 |
6 review(s) available for febuxostat and Blood Pressure, High
| Article | Year |
|---|---|
The Association of Febuxostat Compared With Allopurinol on Blood Pressure and Major Adverse Cardiac Events Among Adult Patients With Hyperuricemia: A Meta-analysis.
Topics: Aged; Allopurinol; Biomarkers; Blood Pressure; Febuxostat; Female; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Treatment Outcome; Uric Acid | 2020 |
The Effect of Xanthine Oxidase Inhibitors on Blood Pressure and Renal Function.
Topics: Allopurinol; Blood Pressure; Enzyme Inhibitors; Febuxostat; Glomerular Filtration Rate; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Renal Insufficiency, Chronic; Treatment Outcome; Uric Acid; Xanthine Oxidase | 2017 |
[Hyperuricaemia and Chronic Kidney Disease].
Topics: Allopurinol; Arteriosclerosis; Disease Progression; Febuxostat; Humans; Hypertension; Hyperuricemia; Observational Studies as Topic; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Risk Factors | 2018 |
Uric Acid: The Unknown Uremic Toxin.
Topics: Allopurinol; Febuxostat; Glomerular Filtration Rate; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Kidney; Parenchymal Tissue; Renal Insufficiency, Chronic; Uric Acid | 2018 |
Cardiovascular Safety of Urate Lowering Therapies.
Topics: Allopurinol; Cardiovascular Diseases; Endothelium; Febuxostat; Gout; Gout Suppressants; Heart Failure; Humans; Hypertension; Hyperuricemia; Myocardial Infarction; Probenecid; Risk; Stroke; Uricosuric Agents; Xanthine Oxidase | 2019 |
[The cutting-edge of medicine; role of hyperuricemia in cardiorenal syndrome].
Topics: Cardio-Renal Syndrome; Febuxostat; Humans; Hypertension; Hyperuricemia; Renal Insufficiency, Chronic; Thiazoles; Treatment Outcome | 2013 |
8 trial(s) available for febuxostat and Blood Pressure, High
| Article | Year |
|---|---|
Urate-lowering drugs for chronic kidney disease with asymptomatic hyperuricemia and hypertension: a randomized trial.
Topics: Benzbromarone; Febuxostat; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Renal Insufficiency, Chronic; Treatment Outcome; Uric Acid | 2023 |
Class effect of xanthine oxidase inhibitors on flow-mediated dilatation in hypertensive patients: A randomized controlled trial.
Topics: Aged; Allopurinol; Dilatation; Febuxostat; Gout; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Treatment Outcome; Xanthine Oxidase | 2020 |
Comparative effects of topiroxostat and febuxostat on arterial properties in hypertensive patients with hyperuricemia.
Topics: Febuxostat; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Nitriles; Pyridines; Treatment Outcome; Uric Acid | 2021 |
Effect of Febuxostat on Ambulatory Blood Pressure in Subjects With Hyperuricemia and Hypertension: A Phase 2 Randomized Placebo-Controlled Study.
Topics: Adult; Aged; Antihypertensive Agents; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Enzyme Inhibitors; Febuxostat; Female; Humans; Hypertension; Hyperuricemia; Male; Middle Aged; North America; Proof of Concept Study; Prospective Studies; Time Factors; Treatment Outcome; Uric Acid; Xanthine Oxidase | 2017 |
Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study.
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Colchicine; Cough; Creatinine; Delayed-Action Preparations; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Febuxostat; Female; gamma-Glutamyltransferase; Glomerular Filtration Rate; Gout; Gout Suppressants; Headache; Humans; Hypertension; Male; Middle Aged; Naproxen; Nasopharyngitis; Renal Insufficiency, Chronic; Respiratory Tract Infections; Severity of Illness Index; Treatment Outcome; Uric Acid | 2019 |
Effect of Febuxostat, a Xanthine Oxidase Inhibitor, on Cardiovascular Risk in Hyperuricemic Patients with Hypertension: A Prospective, Open-label, Pilot Study.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Male; Middle Aged; Pilot Projects; Prospective Studies; Renin-Angiotensin System; Risk Factors; Treatment Outcome; Xanthine Oxidase | 2015 |
Effective uric acid-lowering treatment for hypertensive patients with hyperuricemia.
Topics: Aged; Benzbromarone; Cross-Over Studies; Drug Therapy, Combination; Febuxostat; Female; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Male; Middle Aged; Treatment Outcome; Uric Acid | 2017 |
The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Comorbidity; Dose-Response Relationship, Drug; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperlipidemias; Hypertension; Hyperuricemia; Kidney Diseases; Male; Middle Aged; Obesity; Thiazoles; Treatment Outcome; United States; Uric Acid; Young Adult | 2010 |
14 other study(ies) available for febuxostat and Blood Pressure, High
| Article | Year |
|---|---|
Febuxostat ameliorates high salt intake-induced hypertension and renal damage in Dahl salt-sensitive rats.
Topics: Animals; Blood Pressure; Febuxostat; Hydrogen Peroxide; Hypertension; Kidney; Male; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary | 2022 |
A new Febuxostat-Telmisartan Drug-Drug Cocrystal for Gout-Hypertension Combination Therapy.
Topics: Combined Modality Therapy; Febuxostat; Gout; Humans; Hypertension; Sodium Chloride; Sodium Chloride, Dietary; Telmisartan | 2022 |
Burden and management of gout in a multi-ethnic Asian cohort.
Topics: Adult; Aged; Allopurinol; Comorbidity; Cross-Sectional Studies; Diabetes Mellitus; Dyslipidemias; Emergency Service, Hospital; Ethnicity; Febuxostat; Female; Gout; Gout Suppressants; Hospitalization; Humans; Hypertension; Hyperuricemia; Male; Middle Aged; Probenecid; Renal Insufficiency, Chronic; Severity of Illness Index; Singapore; Treatment Outcome; Uric Acid | 2020 |
High Salt Intake-Increased (Pro)renin Receptor Expression Is Exaggerated in the Kidney of Dahl Salt-Sensitive Rats.
Topics: Animals; Blood Pressure; Febuxostat; Flavoring Agents; Gene Expression Regulation; Hypertension; Mineralocorticoid Receptor Antagonists; Nephrons; Prorenin Receptor; Rats; Rats, Inbred Dahl; Receptors, Cell Surface; Renin-Angiotensin System; Sodium Chloride, Dietary; Spironolactone; Xanthine Oxidase | 2020 |
Association between long-term prescription of febuxostat and the progression of heart failure with preserved ejection fraction in patients with hypertension and asymptomatic hyperuricemia.
Topics: Aged; Asymptomatic Diseases; Biomarkers; Blood Pressure; Databases, Factual; Diastole; Disease Progression; Drug Prescriptions; Febuxostat; Female; Gout Suppressants; Heart Disease Risk Factors; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Hyperuricemia; Male; Middle Aged; Protective Factors; Retrospective Studies; Risk Assessment; Stroke Volume; Time Factors; Uric Acid; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Effect of febuxostat on blood pressure in hyperuricemic patients: A protocol for a systematic review and meta-analysis.
Topics: Blood Pressure; Febuxostat; Humans; Hypertension; Hyperuricemia; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Research Design; Systematic Reviews as Topic | 2020 |
Xanthine oxidase inhibitor febuxostat reduces atrial fibrillation susceptibility by inhibition of oxidized CaMKII in Dahl salt-sensitive rats.
Topics: Allopurinol; Animals; Atrial Fibrillation; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Connexins; Disease Models, Animal; Enzyme Inhibitors; Febuxostat; Fibrosis; Gap Junction alpha-5 Protein; Gap Junctions; Hypertension; Male; Myocytes, Cardiac; Oxidation-Reduction; Phosphorylation; Rats, Inbred Dahl; Ryanodine Receptor Calcium Release Channel; Sodium Chloride, Dietary; Xanthine Oxidase | 2021 |
Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-Induced Aortic Fibrosis.
Topics: Actins; Adventitia; Angiotensin II; Animals; Aorta; Aortic Diseases; Disease Models, Animal; Febuxostat; Fibroblasts; Fibrosis; Gout Suppressants; Hypertension; Macrophages; Male; Mice, Inbred C57BL; Transforming Growth Factor beta1; Vascular Remodeling; Xanthine Oxidase | 2019 |
Xanthine Oxidase Inhibition as a Potential Treatment for Aortic Stiffness in Hypertension.
Topics: Angiotensin II; Febuxostat; Fibrosis; Humans; Hypertension; Macrophages; Vascular Stiffness; Xanthine Oxidase | 2019 |
Prevention of comorbidity and acute attack of gout by uric acid lowering therapy.
Topics: Adult; Allopurinol; Antimetabolites; Benzbromarone; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hypertension; Male; Middle Aged; Renal Insufficiency, Chronic; Retrospective Studies; Thiazoles; Uric Acid; Uricosuric Agents; Urolithiasis | 2014 |
Effects of xanthine oxidase inhibitors on renal function and blood pressure in hypertensive patients with hyperuricemia.
Topics: Aged; Allopurinol; Blood Pressure; Enzyme Inhibitors; Febuxostat; Female; Glomerular Filtration Rate; Humans; Hypertension; Hyperuricemia; Kidney; Male; Middle Aged; Renin-Angiotensin System; Treatment Outcome; Uric Acid; Xanthine Oxidase | 2016 |
Febuxostat, a novel xanthine oxidoreductase inhibitor, improves hypertension and endothelial dysfunction in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Febuxostat; Hypertension; Male; Oxidative Stress; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Tyrosine; Vasodilation; Vasodilator Agents; Xanthine Oxidase | 2016 |
The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012.
Topics: Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; British Columbia; Colchicine; Comorbidity; Diabetes Mellitus; Febuxostat; Female; Glucocorticoids; Gout; Gout Suppressants; Humans; Hyperlipidemias; Hypertension; Incidence; Male; Middle Aged; Population Growth; Prevalence; Probenecid; Sulfinpyrazone; Uricosuric Agents | 2017 |
Long-term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Febuxostat; Hypertension; Male; Rats; Rats, Sprague-Dawley; Thiazoles; Xanthine Oxidase | 2013 |