Page last updated: 2024-09-04

febuxostat and Acute Liver Injury, Drug-Induced

febuxostat has been researched along with Acute Liver Injury, Drug-Induced in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hiramatsu, SI; Ikemura, K; Iwamoto, T; Katayama, N; Nakatani, Y; Okuda, M; Shinogi, Y; Tawara, I1
Chen, J; Deng, Q; Guo, J; Xie, Q; Xie, S; Yu, Y; Zhang, S; Zhong, L1
Kataoka, H; Rock, KL; Yang, K1
Bohm, M; Chalasani, N; Vuppalanchi, R1

Reviews

2 review(s) available for febuxostat and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The association between urate-lowering therapies and treatment-related adverse events, liver damage, and major adverse cardiovascular events (MACE): A network meta-analysis of randomized trials.
    Pharmacotherapy, 2021, Volume: 41, Issue:9

    Topics: Allopurinol; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Network Meta-Analysis; Randomized Controlled Trials as Topic; Uric Acid

2021

Other Studies

4 other study(ies) available for febuxostat and Acute Liver Injury, Drug-Induced

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Concomitant febuxostat enhances methotrexate-induced hepatotoxicity by inhibiting breast cancer resistance protein.
    Scientific reports, 2019, 12-30, Volume: 9, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drug Synergism; Febuxostat; Female; Gout Suppressants; Hematopoiesis; Humans; Kidney; Kidney Function Tests; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Neoplasm Proteins

2019
The xanthine oxidase inhibitor Febuxostat reduces tissue uric acid content and inhibits injury-induced inflammation in the liver and lung.
    European journal of pharmacology, 2015, Jan-05, Volume: 746

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Death; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Enzyme Inhibitors; Febuxostat; Gastroesophageal Reflux; Gout Suppressants; Liver; Lung; Lung Injury; Male; Mice, Inbred C57BL; Necrosis; Neutrophil Infiltration; Peritoneum; Peritonitis; Thiazoles; Uric Acid; Xanthine Oxidase

2015
Febuxostat-induced acute liver injury.
    Hepatology (Baltimore, Md.), 2016, Volume: 63, Issue:3

    Topics: Adult; Chemical and Drug Induced Liver Injury; Febuxostat; Gout Suppressants; Humans; Liver; Male

2016