febrifugine has been researched along with Malaria in 11 studies
*Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiba, T; Kim, HS; Miura, M; Oshima, Y; Takaya, Y; Takeshita, M; Tanitsu, M; Tasaka, H; Uwai, K; Wataya, Y | 1 |
| Hatakeyama, S; Hirai, S; Iwabuchi, Y; Kikuchi, H; Kim, HS; Ooi, H; Oshima, Y; Takaya, Y; Tasaka, H; Wataya, Y | 1 |
| Hariguchi, N; Hirai, S; Horoiwa, S; Kasahara, R; Kikuchi, H; Matsumoto, M; Oshima, Y; Yamamoto, K | 1 |
| Gudise, C; Smith, E; Wei, L; Zeng, Y; Zhang, Q; Zhu, S | 1 |
| Chandrashekar, G; Chatterji, D; Meng, L; Robinson, K; Zhu, S | 1 |
| Ishih, A; Kobayashi, F; Miyase, T; Muregi, FW; Nagata, T; Ohori, K | 1 |
| Ishih, A; Miyase, T; Ohori, K; Terada, M | 1 |
| Ishih, A; Miyase, T; Suzuki, T; Terada, M; Watanabe, M | 1 |
| Ishih, A; Kobayashi, F; Miyase, T; Nagata, T; Terada, M | 1 |
| COATNEY, GR; COOPER, WC; CULWELL, WB; IMBODEN, CA; WHITE, WC | 1 |
| Fushiya, S; Murata, K; Oshima, Y; Takano, F | 1 |
11 other study(ies) available for febrifugine and Malaria
| Article | Year |
|---|---|
New type of febrifugine analogues, bearing a quinolizidine moiety, show potent antimalarial activity against Plasmodium malaria parasite.
Topics: Animals; Antimalarials; Drugs, Chinese Herbal; Malaria; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Conformation; Piperidines; Plasmodium berghei; Plasmodium falciparum; Quinazolines; Quinazolinones; Quinolizines | 1999 |
Potent antimalarial febrifugine analogues against the plasmodium malaria parasite.
Topics: Animals; Antimalarials; Cell Line; Malaria; Mice; Piperidines; Plasmodium berghei; Plasmodium falciparum; Quinazolines; Structure-Activity Relationship | 2002 |
Exploration of a new type of antimalarial compounds based on febrifugine.
Topics: Animals; Antimalarials; Cell Line; Malaria; Mice; Parasitic Sensitivity Tests; Piperidines; Plasmodium berghei; Plasmodium falciparum; Pyrimidinones; Quinazolines; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Toxicity Tests, Acute | 2006 |
Synthesis and biological evaluation of febrifugine analogues as potential antimalarial agents.
Topics: Animals; Antimalarials; Drug Evaluation, Preclinical; Hydrangeaceae; Malaria; Mice; Molecular Structure; Parasitic Sensitivity Tests; Piperidines; Plasmodium falciparum; Quinazolines; Structure-Activity Relationship | 2009 |
Febrifugine analogue compounds: synthesis and antimalarial evaluation.
Topics: Animals; Antimalarials; Aotus trivirgatus; Drug Evaluation, Preclinical; Malaria; Piperidines; Plasmodium falciparum; Quinazolines | 2012 |
Possible involvement of IFN-gamma in early mortality of Plasmodium berghei NK65-infected BALB/c mice after febrifugine treatment.
Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Antimalarials; Interferon-gamma; Interleukin-4; Malaria; Male; Mice; Mice, Inbred BALB C; Parasitemia; Piperidines; Plasmodium berghei; Quinazolines | 2008 |
Different responses of three rodent Plasmodia species, Plasmodium yoelii 17XL, P. berghei NK65 and P. chabaudi AS on treatment with febrifugine and isofebrifugine mixture from Hydrangea macrophylla var. Otaksa leaf in ICR mice.
Topics: Administration, Oral; Animals; Antimalarials; Hydrangea; Malaria; Male; Mice; Mice, Inbred ICR; Parasitic Sensitivity Tests; Phytotherapy; Piperidines; Plant Extracts; Plant Leaves; Plasmodium; Plasmodium berghei; Plasmodium chabaudi; Plasmodium yoelii; Quinazolines | 2003 |
Combination effects of chloroquine with the febrifugine and isofebrifugine mixture against a blood-induced infection with chloroquine-resistant Plasmodium berghei NK65 in ICR mice.
Topics: Animals; Antimalarials; Chloroquine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Malaria; Male; Mice; Mice, Inbred ICR; Parasitic Sensitivity Tests; Phytotherapy; Piperidines; Plasmodium berghei; Quinazolines | 2003 |
Cytokine and antibody production during the course of resolution in Plasmodium yoelii 17XL-infected BALB/c mice treated with febrifugine and isofebrifugine mixture from leaves of Hydrangea macrophylla var. Otaksa.
Topics: Animals; Antibodies, Protozoan; Cytokines; Female; Hydrangea; Malaria; Mice; Mice, Inbred BALB C; Phytotherapy; Piperidines; Plant Leaves; Plasmodium yoelii; Quinazolines | 2004 |
Studies in human malaria. XXV. Trial of febrifugine, an alkaloid obtained from Dichroa febrifuga lour., against the Chesson strain of Plasmodium vivax.
Topics: Alkaloids; Malaria; Piperidines; Plants; Plasmodium vivax; Quinazolines | 1950 |
Potentiation by febrifugine of host defense in mice against Plasmodium berghei NK65.
Topics: Animals; Antimalarials; Drug Interactions; Enzyme Inhibitors; Malaria; Male; Mice; Mice, Inbred ICR; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Parasitemia; Piperidines; Plasmodium berghei; Quinazolines | 1999 |