fasudil has been researched along with Vitreoretinopathy, Proliferative in 2 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Vitreoretinopathy, Proliferative: Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kita, T | 2 |
| Hata, Y | 1 |
| Arita, R | 1 |
| Kawahara, S | 1 |
| Miura, M | 1 |
| Nakao, S | 1 |
| Mochizuki, Y | 1 |
| Enaida, H | 1 |
| Goto, Y | 1 |
| Shimokawa, H | 1 |
| Hafezi-Moghadam, A | 1 |
| Ishibashi, T | 1 |
1 review available for fasudil and Vitreoretinopathy, Proliferative
| Article | Year |
|---|---|
[Molecular mechanisms of preretinal membrane contraction in proliferative vitreoretinal diseases and ROCK as a therapeutic target].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Diabetic Retinopathy; Molecular Targeted The | 2010 |
1 other study available for fasudil and Vitreoretinopathy, Proliferative
| Article | Year |
|---|---|
Role of TGF-beta in proliferative vitreoretinal diseases and ROCK as a therapeutic target.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Blotting, Western; Immunohistochemis | 2008 |