fasudil has been researched along with Syndrome in 1 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study analyzed the morphological, biochemical, and functional features of OPHN1-deficient h-iPSCs and their rescue by treatment with the ROCK inhibitor fasudil, shedding light on the relevance of the ROCK pathway during neuronal differentiation and providing a neuronal model for human OPHN1 syndrome and its treatment." | 3.83 | Rho Kinase Inhibition Is Essential During In Vitro Neurogenesis and Promotes Phenotypic Rescue of Human Induced Pluripotent Stem Cell-Derived Neurons With Oligophrenin-1 Loss of Function. ( Alfieri, P; Barresi, S; Bertini, E; Billuart, P; Chiurazzi, P; Compagnucci, C; Petrini, S; Piccini, G; Zanni, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Compagnucci, C | 1 |
| Barresi, S | 1 |
| Petrini, S | 1 |
| Billuart, P | 1 |
| Piccini, G | 1 |
| Chiurazzi, P | 1 |
| Alfieri, P | 1 |
| Bertini, E | 1 |
| Zanni, G | 1 |
1 other study available for fasudil and Syndrome
| Article | Year |
|---|---|
Rho Kinase Inhibition Is Essential During In Vitro Neurogenesis and Promotes Phenotypic Rescue of Human Induced Pluripotent Stem Cell-Derived Neurons With Oligophrenin-1 Loss of Function.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Differentiation; Cell Shape; Cells, Cultured; Cy | 2016 |