fasudil has been researched along with Retinal Diseases in 4 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Retinal Diseases: Diseases involving the RETINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Retinal ischemia was induced by increasing the intraocular pressure to 100 mmHg for 60 min." | 5.37 | Fasudil, a Rho-associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats. ( Gao, D; Song, H, 2011) |
| "Retinal ischemia was induced by increasing the intraocular pressure to 100 mmHg for 60 min." | 1.37 | Fasudil, a Rho-associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats. ( Gao, D; Song, H, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brockmann, C | 1 |
| Corkhill, C | 1 |
| Jaroslawska, E | 1 |
| Dege, S | 1 |
| Brockmann, T | 1 |
| Kociok, N | 1 |
| Joussen, AM | 1 |
| Wang, H | 1 |
| Chen, X | 1 |
| Song, H | 1 |
| Gao, D | 1 |
| Kita, T | 1 |
| Hata, Y | 1 |
| Kano, K | 1 |
| Miura, M | 1 |
| Nakao, S | 1 |
| Noda, Y | 1 |
| Shimokawa, H | 1 |
| Ishibashi, T | 1 |
4 other studies available for fasudil and Retinal Diseases
| Article | Year |
|---|---|
Systemic Rho-kinase inhibition using fasudil in mice with oxygen-induced retinopathy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Disease Models, Animal; Ma | 2019 |
Effects of a Rho kinase inhibitor on the sequential expression of ICAM-1, HIF-1α, Bcl-2 and caspase-3 in the retina of rats with oxygen-induced retinopathy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Caspase 3; Disease Models, Animal; Gene Expr | 2013 |
Fasudil, a Rho-associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; bcl-2-Associated X Protein; Caspase 3; Gene | 2011 |
Transforming growth factor-beta2 and connective tissue growth factor in proliferative vitreoretinal diseases: possible involvement of hyalocytes and therapeutic potential of Rho kinase inhibitor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Connective Tissue Growth Factor; Gene Expression Regu | 2007 |