Page last updated: 2024-10-28

fasudil and Nephrolithiasis

fasudil has been researched along with Nephrolithiasis in 1 studies

fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.

Nephrolithiasis: Formation of stones in the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
" We develop and utilize a glyoxylate induced mouse model of kidney calcium oxalate crystal deposition for studying the pharmacological effects of fasudil, a Rho associated protein kinase (ROCK) specific inhibitor, on the kidney injury and fibrosis caused by calcium oxalate crystallization and deposition."3.81Fasudil prevents calcium oxalate crystal deposit and renal fibrogenesis in glyoxylate-induced nephrolithic mice. ( Chen, W; Ding, J; Guo, Z; Hu, H; Jia, M; Yin, J, 2015)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hu, H1
Chen, W1
Ding, J1
Jia, M1
Yin, J1
Guo, Z1

Other Studies

1 other study available for fasudil and Nephrolithiasis

ArticleYear
Fasudil prevents calcium oxalate crystal deposit and renal fibrogenesis in glyoxylate-induced nephrolithic mice.
    Experimental and molecular pathology, 2015, Volume: 98, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Apoptosis; Cadherins; Calcium Oxalat

2015