fasudil has been researched along with Myasthenia Gravis in 1 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, J | 1 |
| Xi, JY | 1 |
| Yu, WB | 1 |
| Yan, C | 1 |
| Luo, SS | 1 |
| Zhou, L | 1 |
| Zhu, WH | 1 |
| Lu, JH | 1 |
| Dong, Q | 1 |
| Xiao, BG | 1 |
| Zhao, CB | 1 |
1 other study available for fasudil and Myasthenia Gravis
| Article | Year |
|---|---|
Inhibition of ROCK activity regulates the balance of Th1, Th17 and Treg cells in myasthenia gravis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Disease Models, Animal; Fem | 2019 |