fasudil has been researched along with Malaria, Falciparum in 1 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fasudil was found to be able to prevent endothelium apoptosis from all the P." | 1.36 | Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria. ( Bisvigou, U; Lékana-Douki, JB; Lékoulou, F; Mazier, D; Taoufiq, Z; Touré-Ndouo, FS; Traoré, Y; Zang-Edou, ES, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zang-Edou, ES | 1 |
| Bisvigou, U | 1 |
| Taoufiq, Z | 1 |
| Lékoulou, F | 1 |
| Lékana-Douki, JB | 1 |
| Traoré, Y | 1 |
| Mazier, D | 1 |
| Touré-Ndouo, FS | 1 |
1 other study available for fasudil and Malaria, Falciparum
| Article | Year |
|---|---|
Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adolescent; Animals; Antimalarials; Apoptosis; Cell A | 2010 |