fasudil has been researched along with Kidney Failure, Chronic in 2 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fasudil can restrain EMT induced by PTH; this conclusion provides experimental data for the application of fasudil in the clinical prevention and treatment of renal fibrosis." | 3.85 | The influence of fasudil on renal proximal tubular cell epithelial-mesenchymal transition induced by parathormone. ( Cui, T; Gao, Z; Li, Z; Zhang, H; Zhu, W, 2017) |
| "The fasudil treatment resulted in a significant effect in decreasing TF and PAI-1 [p < 0." | 1.43 | Fasudil inhibits tissue factor and plasminogen activator Inhibitor-1 secretion by peripheral blood mononuclear cells in CAPD patients. ( Chen, W; Fu, K; Han, H; Huang, H; Huang, Y; Li, W; Su, H; Su, Y; Wei, J; Wu, W; Xie, M; Xu, W; Yang, X; Zhang, D; Zhang, Y, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, Z | 1 |
| Zhu, W | 1 |
| Zhang, H | 1 |
| Li, Z | 1 |
| Cui, T | 1 |
| Li, W | 1 |
| Chen, W | 1 |
| Xie, M | 1 |
| Huang, H | 1 |
| Su, H | 1 |
| Han, H | 1 |
| Zhang, D | 1 |
| Zhang, Y | 1 |
| Yang, X | 1 |
| Xu, W | 1 |
| Su, Y | 1 |
| Wu, W | 1 |
| Huang, Y | 1 |
| Fu, K | 1 |
| Wei, J | 1 |
2 other studies available for fasudil and Kidney Failure, Chronic
| Article | Year |
|---|---|
The influence of fasudil on renal proximal tubular cell epithelial-mesenchymal transition induced by parathormone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Antigens, CD; Cadherins; Cell Line; Disease P | 2017 |
Fasudil inhibits tissue factor and plasminogen activator Inhibitor-1 secretion by peripheral blood mononuclear cells in CAPD patients.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Aged; Enzyme-Linked Immunosorbent Assay; Femal | 2016 |