Page last updated: 2024-10-28

fasudil and Corneal Neovascularization

fasudil has been researched along with Corneal Neovascularization in 1 studies

fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.

Corneal Neovascularization: New blood vessels originating from the corneal blood vessels and extending from the limbus into the adjacent CORNEAL STROMA. Neovascularization in the superficial and/or deep corneal stroma is a sequel to numerous inflammatory diseases of the ocular anterior segment, such as TRACHOMA, viral interstitial KERATITIS, microbial KERATOCONJUNCTIVITIS, and the immune response elicited by CORNEAL TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effects and mechanisms of fasudil hydrochloride (fasudil) on and in alkali burn-induced corneal neovascularization (CNV) in mice."7.81Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice. ( Chen, RX; He, H; Li, P; Lin, LM; Pi, RB; Zeng, P; Zhou, SY, 2015)
"To investigate the effects and mechanisms of fasudil hydrochloride (fasudil) on and in alkali burn-induced corneal neovascularization (CNV) in mice."3.81Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice. ( Chen, RX; He, H; Li, P; Lin, LM; Pi, RB; Zeng, P; Zhou, SY, 2015)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zeng, P1
Pi, RB1
Li, P1
Chen, RX1
Lin, LM1
He, H1
Zhou, SY1

Other Studies

1 other study available for fasudil and Corneal Neovascularization

ArticleYear
Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice.
    Molecular vision, 2015, Volume: 21

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkalies; Animals; Burns, Chemical; Corneal Neovascul

2015