Page last updated: 2024-10-28

fasudil and Constriction, Pathological

fasudil has been researched along with Constriction, Pathological in 3 studies

fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.

Research Excerpts

ExcerptRelevanceReference
"Epicardial coronary stenosis causes myocardial ischemia; however, the role of coronary microvessels is poorly understood in the pathogenesis of effort angina."2.73Anti-ischemic effects of fasudil, a specific Rho-kinase inhibitor, in patients with stable effort angina. ( Fukumoto, Y; Hirakawa, Y; Hirooka, Y; Inokuchi, K; Ito, A; Masumoto, A; Mohri, M; Shimokawa, H; Takeshita, A, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, Q1
Wang, J1
Liu, F1
Ma, W1
Hu, H1
Ran, C1
Li, F1
Pan, Q1
Disli, OM1
Ozdemir, E1
Berkan, O1
Bagcivan, I1
Durmus, N1
Parlak, A1
Fukumoto, Y1
Mohri, M1
Inokuchi, K1
Ito, A1
Hirakawa, Y1
Masumoto, A1
Hirooka, Y1
Takeshita, A1
Shimokawa, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study of Telmisartan (Micardis) For the Prevention of Acute Graft vs. Host Disease Post Allogeneic Hematopoietic Stem Cell Transplantation[NCT02338232]32 participants (Actual)Interventional2015-07-07Terminated (stopped due to Lack of Accrual)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for fasudil and Constriction, Pathological

ArticleYear
Anti-ischemic effects of fasudil, a specific Rho-kinase inhibitor, in patients with stable effort angina.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Angina Pectoris; Cardiac Pacing, Artificial; Co

2007

Other Studies

2 other studies available for fasudil and Constriction, Pathological

ArticleYear
A Novel Rabbit Model for Benign Biliary Stricture Formation and the Effects of Medication Infusions on Stricture Formation.
    Digestive diseases and sciences, 2018, Volume: 63, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Agents; Biliary Tract Disease

2018
Rho-kinase inhibitors Y-27632 and fasudil prevent agonist-induced vasospasm in human radial artery.
    Canadian journal of physiology and pharmacology, 2009, Volume: 87, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Amides; Constriction, Pathologic; Dose-Response

2009