Compounds > fasudil
Page last updated: 2024-10-28

fasudil and Cognitive Decline

fasudil has been researched along with Cognitive Decline in 4 studies

fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Tanaka, R3
Liao, J4
Hada, K3
Mori, D3
Nagai, T4
Matsuzaki, T3
Nabeshima, T4
Kaibuchi, K4
Ozaki, N4
Mizoguchi, H4
Yamada, K4
Dong, G1
Zhu, W1
Wulaer, B1
Sawahata, M1
Liu, Y1
Lingli, C1
Hongmei, N1
Penghuan, J1
Hongli, Z1
Yuye, L1
Rui, W1
Fei, R1
Zhihong, Y1
Dongfang, H1
Yaming, G1
Song, X1
He, R1
Han, W1
Li, T1
Xie, L1
Cheng, L1
Chen, H1
Xie, M1
Jiang, L1

Other Studies

4 other studies available for fasudil and Cognitive Decline

ArticleYear
Inhibition of Rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the Arhgap10 gene.
    Pharmacological research, 2023, Volume: 187

    Topics: Animals; Cognitive Dysfunction; Mice; Mutation; Prefrontal Cortex; Protein Kinase Inhibitors; rho-As

2023
Inhibition of Rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the Arhgap10 gene.
    Pharmacological research, 2023, Volume: 187

    Topics: Animals; Cognitive Dysfunction; Mice; Mutation; Prefrontal Cortex; Protein Kinase Inhibitors; rho-As

2023
Inhibition of Rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the Arhgap10 gene.
    Pharmacological research, 2023, Volume: 187

    Topics: Animals; Cognitive Dysfunction; Mice; Mutation; Prefrontal Cortex; Protein Kinase Inhibitors; rho-As

2023
Inhibition of Rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the Arhgap10 gene.
    Pharmacological research, 2023, Volume: 187

    Topics: Animals; Cognitive Dysfunction; Mice; Mutation; Prefrontal Cortex; Protein Kinase Inhibitors; rho-As

2023
Rho kinase inhibitors ameliorate cognitive impairment in a male mouse model of methamphetamine-induced schizophrenia.
    Pharmacological research, 2023, Volume: 194

    Topics: Animals; Clozapine; Cognitive Dysfunction; Haloperidol; Male; Methamphetamine; Mice; Monomeric GTP-B

2023
Inhibition of RhoA/ROCK signalling pathway activity improves neural damage and cognitive deficits in the fluorosis model.
    Ecotoxicology and environmental safety, 2023, Nov-01, Volume: 266

    Topics: Animals; Cognition; Cognitive Dysfunction; Fluorides; Humans; Mice; Mice, Inbred ICR; Neurodegenerat

2023
Protective effects of the ROCK inhibitor fasudil against cognitive dysfunction following status epilepticus in male rats.
    Journal of neuroscience research, 2019, Volume: 97, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Axons; Brain; CA1 Region, Hippocampal; Cogni

2019