fasudil has been researched along with Chronic Kidney Diseases in 3 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We compared the therapeutic effects of fasudil on the spontaneously hypercholesterolemic (SHC) rat, a model of chronic kidney disease (CKD) with proteinuria, with those of the angiotensin receptor blocker olmesartan (OL) by paying attention to the proteinuria and the macrophage phenotype." | 3.79 | Protective effects of Rho kinase inhibitor fasudil on rats with chronic kidney disease. ( Higashi, K; Kumagai, H; Kushiyama, T; Miura, S; Oda, T; Oshima, N; Sakurai, Y; Takechi, H; Uchida, T; Watanabe, A; Yamamoto, K, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kushiyama, T | 1 |
| Oda, T | 1 |
| Yamamoto, K | 1 |
| Higashi, K | 1 |
| Watanabe, A | 1 |
| Takechi, H | 1 |
| Uchida, T | 1 |
| Oshima, N | 1 |
| Sakurai, Y | 1 |
| Miura, S | 1 |
| Kumagai, H | 1 |
| Calò, LA | 1 |
| Vertolli, U | 1 |
| Pagnin, E | 1 |
| Ravarotto, V | 1 |
| Davis, PA | 1 |
| Lupia, M | 1 |
| Naso, E | 1 |
| Maiolino, G | 1 |
| Naso, A | 1 |
| Chu, S | 1 |
| Mao, X | 1 |
| Guo, H | 1 |
| Wang, L | 1 |
| Li, Z | 1 |
| Zhang, Y | 1 |
| Wang, Y | 1 |
| Wang, H | 1 |
| Zhang, X | 1 |
| Peng, W | 1 |
3 other studies available for fasudil and Chronic Kidney Diseases
| Article | Year |
|---|---|
Protective effects of Rho kinase inhibitor fasudil on rats with chronic kidney disease.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Angiotensin II Type 1 Receptor Blockers; Anim | 2013 |
Increased rho kinase activity in mononuclear cells of dialysis and stage 3-4 chronic kidney disease patients with left ventricular hypertrophy: Cardiovascular risk implications.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Aged; Enzyme Activation; Female; Humans; Hyper | 2016 |
Indoxyl sulfate potentiates endothelial dysfunction via reciprocal role for reactive oxygen species and RhoA/ROCK signaling in 5/6 nephrectomized rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Animals; Antioxidants; Cyclic N-Oxides | 2017 |