Page last updated: 2024-10-28

fasudil and Chest Pain

fasudil has been researched along with Chest Pain in 1 studies

fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.

Chest Pain: Pressure, burning, or numbness in the chest.

Research Excerpts

ExcerptRelevanceReference
"The coronary diameter at the concentric stenotic site, which is considered to reflect the whole circumferential atherosclerosis, in patients with stable angina pectoris (SAP; n=11) and the control site in patients with SAP and chest pain syndrome (CPS; n=9), was measured at baseline and after the intracoronary administration of nitroglycerin (200 microg) and the subsequent intravenous infusion of fasudil (30 mg for 30 min), a Rho-kinase inhibitor, during coronary angiography."9.12Vasodilatory effect of subsequent administration of fasudil, a rho-kinase inhibitor, surpasses that of nitroglycerin at the concentric coronary stenosis in patients with stable angina pectoris. ( Atarashi, H; Ibuki, C; Ishii, K; Kishida, H; Kodani, E; Otsuka, T; Suzuki, T; Takano, T, 2006)
"The coronary diameter at the concentric stenotic site, which is considered to reflect the whole circumferential atherosclerosis, in patients with stable angina pectoris (SAP; n=11) and the control site in patients with SAP and chest pain syndrome (CPS; n=9), was measured at baseline and after the intracoronary administration of nitroglycerin (200 microg) and the subsequent intravenous infusion of fasudil (30 mg for 30 min), a Rho-kinase inhibitor, during coronary angiography."5.12Vasodilatory effect of subsequent administration of fasudil, a rho-kinase inhibitor, surpasses that of nitroglycerin at the concentric coronary stenosis in patients with stable angina pectoris. ( Atarashi, H; Ibuki, C; Ishii, K; Kishida, H; Kodani, E; Otsuka, T; Suzuki, T; Takano, T, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Otsuka, T1
Ibuki, C1
Suzuki, T1
Ishii, K1
Kodani, E1
Atarashi, H1
Kishida, H1
Takano, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study of Telmisartan (Micardis) For the Prevention of Acute Graft vs. Host Disease Post Allogeneic Hematopoietic Stem Cell Transplantation[NCT02338232]32 participants (Actual)Interventional2015-07-07Terminated (stopped due to Lack of Accrual)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for fasudil and Chest Pain

ArticleYear
Vasodilatory effect of subsequent administration of fasudil, a rho-kinase inhibitor, surpasses that of nitroglycerin at the concentric coronary stenosis in patients with stable angina pectoris.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Angina Pectoris; Angiography; Chest Pain; Coron

2006