fasudil has been researched along with Carotid Artery Diseases in 5 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Carotid Artery Diseases: Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with valsartan and fasudil prevented the development of vasoconstriction, improved the carotid blood flow and normalized the hypersensitivity to serotonin." | 1.37 | Involvement of Rho-kinase in collar-induced vasoconstriction and vascular hypersensitivity to serotonin in rat carotid. ( Guan, Q; Pang, X; Sun, D; Xie, L; Zeng, D; Zhang, H, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, DJ | 1 |
| Xu, JZ | 1 |
| Wu, YJ | 1 |
| Jean-Charles, L | 1 |
| Xiao, B | 1 |
| Gao, PJ | 1 |
| Zhu, DL | 1 |
| Xie, L | 1 |
| Zeng, D | 1 |
| Zhang, H | 1 |
| Sun, D | 1 |
| Pang, X | 1 |
| Guan, Q | 1 |
| Xie, LN | 1 |
| Zeng, DY | 1 |
| Zhang, HS | 1 |
| Sun, DM | 1 |
| Pang, XF | 1 |
| Guan, QG | 1 |
| Saito, A | 1 |
| Shimizu, H | 1 |
| Doi, Y | 1 |
| Ishida, T | 1 |
| Fujimura, M | 1 |
| Inoue, T | 1 |
| Kiwada, H | 1 |
| Tominaga, T | 1 |
| Fuse, T | 1 |
| Umezu, M | 1 |
| Yamamoto, M | 1 |
| Demura, K | 1 |
| Nishikawa, Y | 1 |
| Niwa, Y | 1 |
5 other studies available for fasudil and Carotid Artery Diseases
| Article | Year |
|---|---|
Effects of fasudil on early atherosclerotic plaque formation and established lesion progression in apolipoprotein E-knockout mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apolipoproteins E; Atherosclerosis; Blood Pr | 2009 |
Involvement of Rho-kinase in collar-induced vasoconstriction and vascular hypersensitivity to serotonin in rat carotid.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II Type 1 Receptor Blockers; Animals; Car | 2011 |
Effect of tongxinluo on vasoconstriction induced by the chronic injury of the adventitia in the rat carotid artery.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carotid Arteries; Carotid Artery Diseases; C | 2010 |
Immunoliposomal drug-delivery system targeting lectin-like oxidized low-density lipoprotein receptor-1 for carotid plaque lesions in rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carotid Artery Diseases; Carotid Artery, Com | 2011 |
External carotid artery aneurysm developing after embolization of a ruptured posterior inferior cerebellar artery aneurysm in a patient with cervicocephalic fibromuscular dysplasia--case report.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Aneurysm, Ruptured; Angiography, Digital Subtr | 2006 |