fasudil has been researched along with Carcinoma in 3 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The poor prognosis of advanced ovarian cancer comes from increased invasiveness of human ovarian cancer cells." | 1.35 | Fasudil inhibits lysophosphatidic acid-induced invasiveness of human ovarian cancer cells. ( Hashimoto, K; Kawase, C; Kimura, T; Mabuchi, S; Morishige, K; Ogata, S; Ooyagi, C; Sakata, M; Sawada, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guerra, FS | 1 |
| Oliveira, RG | 1 |
| Fraga, CAM | 1 |
| Mermelstein, CDS | 1 |
| Fernandes, PD | 1 |
| Ogata, S | 1 |
| Morishige, K | 1 |
| Sawada, K | 1 |
| Hashimoto, K | 1 |
| Mabuchi, S | 1 |
| Kawase, C | 1 |
| Ooyagi, C | 1 |
| Sakata, M | 1 |
| Kimura, T | 1 |
| Yang, X | 1 |
| Zhang, Y | 1 |
| Wang, S | 1 |
| Shi, W | 1 |
3 other studies available for fasudil and Carcinoma
| Article | Year |
|---|---|
ROCK inhibition with Fasudil induces beta-catenin nuclear translocation and inhibits cell migration of MDA-MB 231 human breast cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antineoplastic Agents; beta Catenin; Carcinoma; Cell | 2017 |
Fasudil inhibits lysophosphatidic acid-induced invasiveness of human ovarian cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Agents; Carcinoma; Cell Movem | 2009 |
Effect of fasudil on growth, adhesion, invasion, and migration of 95D lung carcinoma cells in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antineoplastic Agents; Carcinoma; Cell Adhesion; Cell | 2010 |