fasudil has been researched along with Cancer of Prostate in 3 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human prostate cancer cell lines PC3 and DU145 were treated with fasudil at the concentrations of 5, 10, 20, 40, 80, and 160 μmol/L, respectively, and those as negative controls cultured in the Ham's-F12 medium, all for 24 hours." | 1.43 | [Effects of the Rho-kinase inhibitor fasudil on the invasion, migration, and apoptosis of human prostate cancer PC3 and DU145 cells]. ( Chen, H; Chen, Y; Dai, YT; Gao, QQ; Han, YF; Xu, ZP; Yu, W; Zhu, LL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, QQ | 1 |
| Chen, H | 1 |
| Chen, Y | 1 |
| Xu, ZP | 1 |
| Zhu, LL | 1 |
| Yu, W | 1 |
| Han, YF | 1 |
| Dai, YT | 1 |
| Chen, W | 1 |
| Mao, K | 1 |
| Hua-Huy, T | 1 |
| Bei, Y | 1 |
| Liu, Z | 1 |
| Dinh-Xuan, AT | 1 |
| Tang, AT | 1 |
| Campbell, WB | 1 |
| Nithipatikom, K | 1 |
3 other studies available for fasudil and Cancer of Prostate
| Article | Year |
|---|---|
[Effects of the Rho-kinase inhibitor fasudil on the invasion, migration, and apoptosis of human prostate cancer PC3 and DU145 cells].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Prol | 2016 |
Fasudil inhibits prostate cancer-induced angiogenesis in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Line, Tumor; Cell Movement; Cell Proliferation; | 2014 |
ROCK1 feedback regulation of the upstream small GTPase RhoA.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; ADP Ribose Transferases; Amides; | 2012 |