Page last updated: 2024-10-28

fasudil and Bright Disease

fasudil has been researched along with Bright Disease in 2 studies

fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.

Bright Disease: A historical classification which is no longer used. It described acute glomerulonephritis, acute nephritic syndrome, or acute nephritis. Named for Richard Bright.

Research Excerpts

ExcerptRelevanceReference
"Fasudil treatment significantly improved survival and decreased proteinuria, particularly when treatment was started at 18 weeks."1.38Administration of fasudil, a ROCK inhibitor, attenuates disease in lupus-prone NZB/W F1 female mice. ( Bhagat, G; Biswas, PS; Gupta, S; Pernis, AB; Song, L; Stirzaker, RA, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stirzaker, RA1
Biswas, PS1
Gupta, S1
Song, L1
Bhagat, G1
Pernis, AB1
Hidaka, T1
Suzuki, Y1
Yamashita, M1
Shibata, T1
Tanaka, Y1
Horikoshi, S1
Tomino, Y1

Other Studies

2 other studies available for fasudil and Bright Disease

ArticleYear
Administration of fasudil, a ROCK inhibitor, attenuates disease in lupus-prone NZB/W F1 female mice.
    Lupus, 2012, Volume: 21, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Administration, Oral; Animals; Antigen-Antibody Compl

2012
Amelioration of crescentic glomerulonephritis by RhoA kinase inhibitor, Fasudil, through podocyte protection and prevention of leukocyte migration.
    The American journal of pathology, 2008, Volume: 172, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Pressure; Blood Urea Nitrogen; Cells,

2008