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fasudil and Aortic Aneurysm, Abdominal

fasudil has been researched along with Aortic Aneurysm, Abdominal in 1 studies

fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.

Aortic Aneurysm, Abdominal: An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.

Research Excerpts

ExcerptRelevanceReference
"Angiotensin II (Ang II) accelerates atherosclerosis and induces abdominal aortic aneurysm (AAA) in an experimental mouse model."7.73Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis. ( da Cunha, V; Deng, GD; Dole, WP; Feng, Q; Halks-Miller, M; Johns, A; Kauser, K; Light, DR; Lu, X; Mahmoudi, M; Martin-McNulty, B; Schirm, S; Schroeder, M; Subramanyam, B; Tseng, JL; Vincelette, J; Wang, YX, 2005)
"Angiotensin II (Ang II) accelerates atherosclerosis and induces abdominal aortic aneurysm (AAA) in an experimental mouse model."3.73Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis. ( da Cunha, V; Deng, GD; Dole, WP; Feng, Q; Halks-Miller, M; Johns, A; Kauser, K; Light, DR; Lu, X; Mahmoudi, M; Martin-McNulty, B; Schirm, S; Schroeder, M; Subramanyam, B; Tseng, JL; Vincelette, J; Wang, YX, 2005)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, YX1
Martin-McNulty, B1
da Cunha, V1
Vincelette, J1
Lu, X1
Feng, Q1
Halks-Miller, M1
Mahmoudi, M1
Schroeder, M1
Subramanyam, B1
Tseng, JL1
Deng, GD1
Schirm, S1
Johns, A1
Kauser, K1
Dole, WP1
Light, DR1

Other Studies

1 other study available for fasudil and Aortic Aneurysm, Abdominal

ArticleYear
Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis.
    Circulation, 2005, May-03, Volume: 111, Issue:17

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aortic Aneurysm, Abdominal;

2005