fasudil and Alcoholism
fasudil has been researched along with Alcoholism in 1 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alcohol dependence is a chronic, relapsing encephalopathy characterized by compulsive craving for alcohol, loss of control over alcohol use, and the presence of negative emotions and physical discomfort when alcohol is unavailable." | 1.91 | Fasudil may alleviate alcohol-induced astrocyte damage by modifying lipid metabolism, as determined by metabonomics analysis. ( Bai, S; Huang, X; Li, X; Qi, X; Sun, G; Wu, C; Zhao, H; Zheng, Y; Zhu, X, 2023) |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Zhao, H | 1 |
| Li, X | 1 |
| Zheng, Y | 1 |
| Zhu, X | 1 |
| Qi, X | 1 |
| Huang, X | 1 |
| Bai, S | 1 |
| Wu, C | 1 |
| Sun, G | 1 |
Other Studies
1 other study available for fasudil and Alcoholism
| Article | Year |
|---|---|
Fasudil may alleviate alcohol-induced astrocyte damage by modifying lipid metabolism, as determined by metabonomics analysis.
Topics: Alcoholism; Astrocytes; Ethanol; Humans; Lipid Metabolism; Metabolomics | 2023 |