fasudil has been researched along with Acute Brain Injuries in 4 studies
fasudil: intracellular calcium antagonist; structure in first source
fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we used the model of hypoxia/reoxygenation (H/R) injury to explore the possibility whether Fasudil, a ROCK inhibitor in clinical application for subarachnoid hemorrhage and stroke, mobilizes adult neural stem cells in vivo." | 7.76 | Fasudil, a Rho kinase inhibitor, drives mobilization of adult neural stem cells after hypoxia/reoxygenation injury in mice. ( Ding, J; Li, QY; Lu, CZ; Sun, CH; Wang, X; Xiao, BG; Yu, JZ, 2010) |
| " Here, we used the model of hypoxia/reoxygenation (H/R) injury to explore the possibility whether Fasudil, a ROCK inhibitor in clinical application for subarachnoid hemorrhage and stroke, mobilizes adult neural stem cells in vivo." | 3.76 | Fasudil, a Rho kinase inhibitor, drives mobilization of adult neural stem cells after hypoxia/reoxygenation injury in mice. ( Ding, J; Li, QY; Lu, CZ; Sun, CH; Wang, X; Xiao, BG; Yu, JZ, 2010) |
| "Ischemic stroke is a deleterious cerebrovascular disease with few therapeutic options, and its functional recovery is highly associated with the integrity of the blood-brain barrier and neuroinflammation." | 1.91 | FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke. ( Guan, X; Huang, Z; Liang, Z; Pang, T; Wang, Y; Wei, D; Wu, J; Xie, L, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guan, X | 1 |
| Wei, D | 1 |
| Liang, Z | 1 |
| Xie, L | 1 |
| Wang, Y | 1 |
| Huang, Z | 1 |
| Wu, J | 1 |
| Pang, T | 1 |
| Fan, R | 1 |
| Enkhjargal, B | 1 |
| Camara, R | 1 |
| Yan, F | 1 |
| Gong, L | 1 |
| Tang, J | 1 |
| Chen, Y | 1 |
| Zhang, JH | 1 |
| Ding, J | 1 |
| Li, QY | 1 |
| Yu, JZ | 1 |
| Wang, X | 1 |
| Sun, CH | 1 |
| Lu, CZ | 1 |
| Xiao, BG | 1 |
| Alford, PW | 1 |
| Dabiri, BE | 1 |
| Goss, JA | 1 |
| Hemphill, MA | 1 |
| Brigham, MD | 1 |
| Parker, KK | 1 |
4 other studies available for fasudil and Acute Brain Injuries
| Article | Year |
|---|---|
FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke.
Topics: Animals; Blood-Brain Barrier; Brain Injuries; Brain Ischemia; Humans; Infarction, Middle Cerebral Ar | 2023 |
Critical role of EphA4 in early brain injury after subarachnoid hemorrhage in rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood-Brain Barrier; Brain; Brain Edema; Bra | 2017 |
Fasudil, a Rho kinase inhibitor, drives mobilization of adult neural stem cells after hypoxia/reoxygenation injury in mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult Stem Cells; Animals; Antibodies; Astrocytes; Br | 2010 |
Blast-induced phenotypic switching in cerebral vasospasm.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Algorithms; Arteries; Blast Injuries; Blotting, Weste | 2011 |