farnesol has been researched along with Leukemia in 5 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (80.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Badar, T; Borthakur, G; Cortes, JE; Garcia-Manero, G; Kantarjian, H; O'Brien, S; Ravandi, F; Verstovsek, S | 1 |
Haug, JS; Melnykovych, G; Voziyan, PA | 1 |
Goldner, CM; Melnykovych, G; Voziyan, PA | 1 |
Katagiri, T; Kizaki, M; Miyazawa, K; Nishimaki, J; Tohyama, K; Toyama, K; Yaguchi, M | 1 |
Cermak, DM; Hohl, RJ; Lewis, KA; Wiemer, DF | 1 |
1 trial(s) available for farnesol and Leukemia
Article | Year |
---|---|
Phase I study of S-trans, trans-farnesylthiosalicylic acid (salirasib), a novel oral RAS inhibitor in patients with refractory hematologic malignancies.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Farnesol; Female; Genes, ras; Humans; Leukemia; Male; Middle Aged; Neoplasm Recurrence, Local; raf Kinases; Salicylates; Signal Transduction; Transcriptional Activation; Treatment Outcome | 2015 |
4 other study(ies) available for farnesol and Leukemia
Article | Year |
---|---|
Mechanism of farnesol cytotoxicity: further evidence for the role of PKC-dependent signal transduction in farnesol-induced apoptotic cell death.
Topics: Acute Disease; Apoptosis; Cell Division; Choline; Diglycerides; DNA; Farnesol; Humans; Leukemia; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases | 1995 |
Farnesol inhibits phosphatidylcholine biosynthesis in cultured cells by decreasing cholinephosphotransferase activity.
Topics: Choline; Choline-Phosphate Cytidylyltransferase; Diacylglycerol Cholinephosphotransferase; Diglycerides; Farnesol; Humans; Leukemia; Lipid Metabolism; Nucleotidyltransferases; Phosphatidylcholines; Tumor Cells, Cultured | 1993 |
Vitamin K2 and its derivatives induce apoptosis in leukemia cells and enhance the effect of all-trans retinoic acid.
Topics: Apoptosis; Bone Marrow; Diterpenes; Drug Synergism; Farnesol; Flow Cytometry; Gefarnate; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Molecular Structure; Myelodysplastic Syndromes; Structure-Activity Relationship; Tretinoin; Tumor Cells, Cultured; Vitamin K; Vitamin K 1; Vitamin K 2 | 1997 |
Stereochemistry-dependent inhibition of RAS farnesylation by farnesyl phosphonic acids.
Topics: Alkyl and Aryl Transferases; Cholesterol; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Humans; Leukemia; Molecular Conformation; Organophosphonates; Protein Prenylation; ras Proteins; Structure-Activity Relationship; Substrate Specificity; Tumor Cells, Cultured | 1998 |