farnesol and Leukemia

farnesol has been researched along with Leukemia in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Badar, T; Borthakur, G; Cortes, JE; Garcia-Manero, G; Kantarjian, H; O'Brien, S; Ravandi, F; Verstovsek, S1
Haug, JS; Melnykovych, G; Voziyan, PA1
Goldner, CM; Melnykovych, G; Voziyan, PA1
Katagiri, T; Kizaki, M; Miyazawa, K; Nishimaki, J; Tohyama, K; Toyama, K; Yaguchi, M1
Cermak, DM; Hohl, RJ; Lewis, KA; Wiemer, DF1

Trials

1 trial(s) available for farnesol and Leukemia

ArticleYear
Phase I study of S-trans, trans-farnesylthiosalicylic acid (salirasib), a novel oral RAS inhibitor in patients with refractory hematologic malignancies.
    Clinical lymphoma, myeloma & leukemia, 2015, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Farnesol; Female; Genes, ras; Humans; Leukemia; Male; Middle Aged; Neoplasm Recurrence, Local; raf Kinases; Salicylates; Signal Transduction; Transcriptional Activation; Treatment Outcome

2015

Other Studies

4 other study(ies) available for farnesol and Leukemia

ArticleYear
Mechanism of farnesol cytotoxicity: further evidence for the role of PKC-dependent signal transduction in farnesol-induced apoptotic cell death.
    Biochemical and biophysical research communications, 1995, Jul-17, Volume: 212, Issue:2

    Topics: Acute Disease; Apoptosis; Cell Division; Choline; Diglycerides; DNA; Farnesol; Humans; Leukemia; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases

1995
Farnesol inhibits phosphatidylcholine biosynthesis in cultured cells by decreasing cholinephosphotransferase activity.
    The Biochemical journal, 1993, Nov-01, Volume: 295 ( Pt 3)

    Topics: Choline; Choline-Phosphate Cytidylyltransferase; Diacylglycerol Cholinephosphotransferase; Diglycerides; Farnesol; Humans; Leukemia; Lipid Metabolism; Nucleotidyltransferases; Phosphatidylcholines; Tumor Cells, Cultured

1993
Vitamin K2 and its derivatives induce apoptosis in leukemia cells and enhance the effect of all-trans retinoic acid.
    Leukemia, 1997, Volume: 11, Issue:6

    Topics: Apoptosis; Bone Marrow; Diterpenes; Drug Synergism; Farnesol; Flow Cytometry; Gefarnate; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Molecular Structure; Myelodysplastic Syndromes; Structure-Activity Relationship; Tretinoin; Tumor Cells, Cultured; Vitamin K; Vitamin K 1; Vitamin K 2

1997
Stereochemistry-dependent inhibition of RAS farnesylation by farnesyl phosphonic acids.
    Lipids, 1998, Volume: 33, Issue:1

    Topics: Alkyl and Aryl Transferases; Cholesterol; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Humans; Leukemia; Molecular Conformation; Organophosphonates; Protein Prenylation; ras Proteins; Structure-Activity Relationship; Substrate Specificity; Tumor Cells, Cultured

1998