Page last updated: 2024-10-26

famotidine and Stomach Neoplasms

famotidine has been researched along with Stomach Neoplasms in 14 studies

Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.

Stomach Neoplasms: Tumors or cancer of the STOMACH.

Research Excerpts

ExcerptRelevanceReference
" This study aimed to compare the effects of omeprazole and famotidine on ulcer healing and fibroblast growth factor-2 levels in gastric ulcers induced by endoscopic mucosal resection."9.10Effects of omeprazole and famotidine on fibroblast growth factor-2 during artificial gastric ulcer healing in humans. ( Aoyagi, K; Esaki, M; Fujishima, M; Kuwano, Y; Matsumoto, T; Shimizu, M, 2002)
"A total of 158 patients (155 early gastric cancers and three adenomas) were randomly assigned to the PPI group (omeprazole 20 mg/day) or H(2) RA group (famotidine 40 mg/day) in a prospective randomized controlled trial."5.16Prospective randomized controlled trial to compare the effects of omeprazole and famotidine in preventing delayed bleeding and promoting ulcer healing after endoscopic submucosal dissection. ( Fukui, H; Hori, K; Kim, Y; Kondo, T; Matsumoto, T; Miwa, H; Morita, T; Okugawa, T; Oshima, T; Sakurai, J; Tanaka, J; Tomita, T; Toyoshima, F; Watari, J; Yamasaki, T, 2012)
" This study aimed to compare the effects of omeprazole and famotidine on ulcer healing and fibroblast growth factor-2 levels in gastric ulcers induced by endoscopic mucosal resection."5.10Effects of omeprazole and famotidine on fibroblast growth factor-2 during artificial gastric ulcer healing in humans. ( Aoyagi, K; Esaki, M; Fujishima, M; Kuwano, Y; Matsumoto, T; Shimizu, M, 2002)
" Subjects underwent EMR with circumferential mucosal incision assisted by submucosal injection of sodium hyaluronate (EMRSH), followed by IV or oral (PO) administration of famotidine at a dosage of 40 mg/day for 2 days."2.71Comparison of hemostatic effects by route of H2 receptor antagonist administration following endoscopic mucosal resection in patients with neoplastic gastric lesions. ( Ajibe, H; Hanatsuka, K; Hirasawa, T; Kawata, H; Kita, H; Osawa, H; Satoh, K; Satoh, Y; Sugano, K; Sunada, F; Sunada, K; Yamamoto, H; Yoshizawa, M, 2005)
"Subjects with gastric cancer showed significantly higher levels of suppressor lymphocyte activity than normal controls."1.29Comparison of immunomodulative effects of the histamine-2 receptor antagonists cimetidine, ranitidine, and famotidine on peripheral blood mononuclear cells in gastric cancer patients. ( Hahm, KB; Kang, JK; Kim, WH; Lee, SI; Park, IS, 1995)
"Famotidine has no action on membrane components activating the adenylate cyclase system, including the Gs subunit of the enzyme stimulated by forskolin and cell surface receptors sensitive to isoproterenol (beta 2-type), PGE2 and VIP."1.28Pharmacological control of the human gastric histamine H2 receptor by famotidine: comparison with H1, H2 and H3 receptor agonists and antagonists. ( Emami, S; Fagot, D; Gespach, C, 1989)
"In the HGT-1 human gastric cancer cell line, famotidine and ranitidine showed long lasting, irreversible actions probably related to a slow rate of dissociation from the histamine H2-receptor."1.27Pharmacological control of the histamine H2 receptor-adenylate cyclase system by famotidine and ranitidine in normal and cancerous human gastric epithelia. ( Bawab, W; Chastre, E; Emami, S; Fagot, D; Gespach, C, 1988)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's5 (35.71)18.2507
2000's5 (35.71)29.6817
2010's1 (7.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Huang, J1
Fan, P1
Liu, M1
Weng, C1
Fan, G1
Zhang, T1
Duan, X1
Wu, Y1
Tang, L1
Yang, G1
Liu, Y1
Tomita, T1
Kim, Y1
Yamasaki, T1
Okugawa, T1
Kondo, T1
Toyoshima, F1
Sakurai, J1
Tanaka, J2
Morita, T1
Oshima, T1
Fukui, H1
Hori, K1
Watari, J1
Matsumoto, T2
Miwa, H1
Yamaguchi, Y1
Katsumi, N1
Tauchi, M1
Toki, M1
Nakamura, K1
Aoki, K1
Morita, Y1
Miura, M1
Morozumi, K1
Ishida, H1
Takahashi, S1
Satoh, K1
Yamamoto, H1
Kawata, H1
Osawa, H1
Hanatsuka, K1
Kita, H1
Sunada, K1
Hirasawa, T1
Yoshizawa, M1
Ajibe, H1
Satoh, Y1
Sunada, F1
Sugano, K1
Ye, BD1
Cheon, JH1
Choi, KD1
Kim, SG1
Kim, JS1
Jung, HC1
Song, IS1
Jeong, HK1
Park, CH1
Jun, CH1
Lee, GH1
Kim, HI1
Kim, HS1
Choi, SK1
Rew, JS1
Hahm, KB1
Kim, WH1
Lee, SI1
Kang, JK1
Park, IS1
Fujimoto, K1
Iwakiri, R1
Koyama, T1
Sakata, H1
Ohyama, T1
Mizuguchi, M1
Tokunaga, O1
Haga, Y1
Nakatsura, T1
Shibata, Y1
Sameshima, H1
Nakamura, Y1
Tanimura, M1
Ogawa, M1
Dogăn, UB1
Tunçer, C1
Dursun, A1
Kandilci, U1
Esaki, M1
Aoyagi, K1
Kuwano, Y1
Shimizu, M1
Fujishima, M1
Isobe, Y1
Nagai, H1
Muramatsu, M1
Aihara, H1
Otomo, S1
Gespach, C2
Fagot, D2
Emami, S2
Chastre, E1
Bawab, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study[NCT02081404]98 participants (Actual)Interventional2009-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for famotidine and Stomach Neoplasms

ArticleYear
Prospective randomized controlled trial to compare the effects of omeprazole and famotidine in preventing delayed bleeding and promoting ulcer healing after endoscopic submucosal dissection.
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:9

    Topics: Adenocarcinoma; Adenoma; Aged; Aged, 80 and over; Analysis of Variance; Famotidine; Female; Gastric

2012
A prospective randomized trial of either famotidine or omeprazole for the prevention of bleeding after endoscopic mucosal resection and the healing of endoscopic mucosal resection-induced ulceration.
    Alimentary pharmacology & therapeutics, 2005, Volume: 21 Suppl 2

    Topics: Aged; Anti-Ulcer Agents; Cost-Benefit Analysis; Endoscopy, Gastrointestinal; Famotidine; Female; Gas

2005
Comparison of hemostatic effects by route of H2 receptor antagonist administration following endoscopic mucosal resection in patients with neoplastic gastric lesions.
    Alimentary pharmacology & therapeutics, 2005, Volume: 21 Suppl 2

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Administration, Oral; Aged; Endoscopy, Gastrointestinal; Fam

2005
Omeprazole may be superior to famotidine in the management of iatrogenic ulcer after endoscopic mucosal resection: a prospective randomized controlled trial.
    Alimentary pharmacology & therapeutics, 2006, Sep-01, Volume: 24, Issue:5

    Topics: Anti-Ulcer Agents; Famotidine; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Hum

2006
A prospective randomized trial of either famotidine or pantoprazole for the prevention of bleeding after endoscopic submucosal dissection.
    Journal of Korean medical science, 2007, Volume: 22, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Ulcer Agents; Dissection; Famotidine; Female; Ga

2007
Effects of omeprazole and famotidine on fibroblast growth factor-2 during artificial gastric ulcer healing in humans.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:4

    Topics: Aged; Anti-Ulcer Agents; Endoscopy; Famotidine; Female; Fibroblast Growth Factor 2; Humans; Male; Mi

2002

Other Studies

8 other studies available for famotidine and Stomach Neoplasms

ArticleYear
Famotidine promotes inflammation by triggering cell pyroptosis in gastric cancer cells.
    BMC pharmacology & toxicology, 2021, 10-22, Volume: 22, Issue:1

    Topics: Anti-Ulcer Agents; Cell Line, Tumor; Famotidine; Histamine H2 Antagonists; Humans; Inflammasomes; In

2021
Comparison of immunomodulative effects of the histamine-2 receptor antagonists cimetidine, ranitidine, and famotidine on peripheral blood mononuclear cells in gastric cancer patients.
    Scandinavian journal of gastroenterology, 1995, Volume: 30, Issue:3

    Topics: Adjuvants, Immunologic; Case-Control Studies; Cimetidine; Cytotoxicity Tests, Immunologic; Famotidin

1995
Hyperplastic polyps following treatment of acute gastric ulcers.
    Internal medicine (Tokyo, Japan), 1994, Volume: 33, Issue:6

    Topics: Esophageal and Gastric Varices; Famotidine; Female; Humans; Hyperplasia; Middle Aged; Omeprazole; Po

1994
Human gastric carcinoid detected during long-term antiulcer therapy of H2 receptor antagonist and proton pump inhibitor.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Carcinoid Tumor; Famotidine; Hist

1998
Effect of chronic acid inhibition on duodenal bulb gastric metaplasia and Helicobacter pylori.
    Italian journal of gastroenterology and hepatology, 1998, Volume: 30, Issue:2

    Topics: Adult; Case-Control Studies; Duodenal Ulcer; Duodenum; Famotidine; Female; Gastric Mucosa; Helicobac

1998
Antisecretory and antilesional effect of a new histamine H2-receptor antagonist, IT-066, in rats.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Animals; Cimetidine; Cold Temperature; Cysteamine; Dose-Response Relationship, Drug; Duodenal Neopla

1990
Pharmacological control of the human gastric histamine H2 receptor by famotidine: comparison with H1, H2 and H3 receptor agonists and antagonists.
    European journal of clinical investigation, 1989, Volume: 19, Issue:1

    Topics: Adenylyl Cyclases; Cyclic AMP; Famotidine; Gastric Fundus; Histamine; Histamine H2 Antagonists; Huma

1989
Pharmacological control of the histamine H2 receptor-adenylate cyclase system by famotidine and ranitidine in normal and cancerous human gastric epithelia.
    Agents and actions, 1988, Volume: 23, Issue:3-4

    Topics: Adenylyl Cyclases; Epithelium; Famotidine; Gastric Fundus; Humans; In Vitro Techniques; Ranitidine;

1988