famotidine has been researched along with Parkinson Disease in 3 studies
Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seven patients with idiopathic Parkinson's disease were enrolled in a ten week study to evaluate the efficacy of famotidine, an histamine H2-antagonist, in the treatment of bradyphrenia." | 2.68 | The use of famotidine in the treatment of Parkinson's disease: a pilot study. ( Di Rocco, A; Kaminski, R; Molinari, SP; Yahr, MD, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lim, SAO | 1 |
| Xia, R | 1 |
| Ding, Y | 1 |
| Won, L | 1 |
| Ray, WJ | 1 |
| Hitchcock, SA | 1 |
| McGehee, DS | 1 |
| Kang, UJ | 1 |
| Molinari, SP | 1 |
| Kaminski, R | 1 |
| Di Rocco, A | 1 |
| Yahr, MD | 1 |
| Katsumata, S | 1 |
| Mizuno, S | 1 |
| Shirata, A | 1 |
| Yamane, K | 1 |
1 trial available for famotidine and Parkinson Disease
| Article | Year |
|---|---|
The use of famotidine in the treatment of Parkinson's disease: a pilot study.
Topics: Aged; Cognition; Famotidine; Histamine H2 Antagonists; Humans; Middle Aged; Neuropsychological Tests | 1995 |
2 other studies available for famotidine and Parkinson Disease
| Article | Year |
|---|---|
Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesia.
Topics: Action Potentials; Animals; Cholinergic Neurons; Corpus Striatum; Dicyclomine; Disease Models, Anima | 2015 |
[Famotidine induced parkinsonism in a case of essential tremor].
Topics: Aged; Essential Tremor; Famotidine; Female; Histamine H2 Antagonists; Humans; Parkinson Disease | 2002 |