famotidine has been researched along with Muscle Contraction in 12 studies
Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The regular dosage of cimetidine showed an inhibitory effect on the motility of SO, while famotidine had no obvious effects otherwise." | 2.73 | Choledochoscope manometry about different drugs on the Sphincter of Oddi. ( Chen, JZ; Kong, J; Li, ZS; Shi, G; Wang, W; Wu, SD; Zhang, XB, 2008) |
| " In the guinea pig ileum, millimolar concentrations of cimetidine and famotidine shifted the dose-response curve of the contractile response to acetylcholine rightward." | 1.29 | Comparative effects of cimetidine and famotidine on the vagally stimulated acid secretion in the isolated mouse whole stomach. ( Kanaoka, S; Watanabe, K; Yamamoto, M; Yano, S, 1993) |
| " However, when the preparations were precontracted with histamine (10(-5)M), dose-response curves for relaxation were shifted to the right, and low-concentrations of all three histamine H2-antagonists augmented histamine-induced tone." | 1.27 | Direct effects of H2-receptor antagonists on airway smooth muscle and on responses mediated by H1- and H2-receptors. ( Hashimoto, Y; Iwatsuki, N; Koga, Y, 1987) |
| "Famotidine was highly effective (approximately 10 times as potent as ranitidine) also on the rat uterus (unsurmountable antagonism) and on the guinea pig gallbladder (pA2 value = 7." | 1.27 | Pharmacology of the novel H2 antagonist famotidine: in vitro studies. ( Adami, M; Bertaccini, G; Coruzzi, G; Poli, E, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kong, J | 1 |
| Wu, SD | 1 |
| Zhang, XB | 1 |
| Li, ZS | 1 |
| Shi, G | 1 |
| Wang, W | 1 |
| Chen, JZ | 1 |
| Koutsoviti-Papadopoulou, M | 2 |
| Nikolaidis, E | 1 |
| Kounenis, G | 2 |
| Jeong, JH | 1 |
| Yun, MC | 1 |
| Shin, CY | 1 |
| Lee, TS | 1 |
| Song, HJ | 1 |
| Sohn, UD | 1 |
| Matsunaga, Y | 2 |
| Yamamoto, O | 2 |
| Ueki, S | 1 |
| Haga, N | 2 |
| Mizusawa, F | 1 |
| Mizumoto, A | 1 |
| Sano, I | 2 |
| Itoh, Z | 2 |
| Shiba, Y | 1 |
| Watanabe, K | 1 |
| Yano, S | 1 |
| Yamamoto, M | 1 |
| Kanaoka, S | 1 |
| Coruzzi, G | 2 |
| Pozzoli, C | 1 |
| Poli, E | 2 |
| Coppelli, G | 1 |
| Bertaccini, G | 2 |
| Elezoglou, A | 1 |
| Voutsas, A | 1 |
| Shibata, M | 1 |
| Yamaura, T | 1 |
| Sekine, A | 1 |
| Nishikawa, M | 1 |
| Chida, Y | 1 |
| Ohnishi, H | 1 |
| Aono, M | 1 |
| Moriga, M | 1 |
| Mizuta, K | 1 |
| Narusawa, H | 1 |
| Koga, Y | 1 |
| Iwatsuki, N | 1 |
| Hashimoto, Y | 1 |
| Adami, M | 1 |
1 trial available for famotidine and Muscle Contraction
| Article | Year |
|---|---|
Choledochoscope manometry about different drugs on the Sphincter of Oddi.
Topics: Adult; Aged; Aged, 80 and over; Benzamides; Cholecystectomy; Cimetidine; Domperidone; Endoscopes; Fa | 2008 |
11 other studies available for famotidine and Muscle Contraction
| Article | Year |
|---|---|
Enhancing and inhibitory effects of H2-receptor antagonists on the GABA and the GABAA-agonist muscimol responses of the isolated guinea pig ileum: a pharmacodynamic interaction.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Famotidine; Female; GABA A | 2003 |
Signaling via histamine receptors in cat duodenal smooth muscle cells.
Topics: Alkaloids; Animals; Benzophenanthridines; Cats; Duodenum; Enzyme Inhibitors; Ethylmaleimide; Famotid | 2003 |
Inhibition of phase III activity by acid in canine stomach.
Topics: Animals; Disease Models, Animal; Dogs; Duodenal Ulcer; Electrodes; Electrophysiology; Famotidine; Fe | 1994 |
Inhibition of motilin-induced phase III contractions by pentagastrin in Heidenhain pouch dogs.
Topics: Animals; Benzodiazepinones; Devazepide; Dogs; Famotidine; Gastric Acidity Determination; Motilin; Mu | 1994 |
Comparative effects of cimetidine and famotidine on the vagally stimulated acid secretion in the isolated mouse whole stomach.
Topics: Acetylcholine; Animals; Cimetidine; Drug Interactions; Electric Stimulation; Famotidine; Gastric Aci | 1993 |
Effects of histamine H2 receptor agonists and antagonists on the isolated guinea pig gallbladder.
Topics: Animals; Benzothiazoles; Dopamine Agents; Famotidine; Gallbladder; Guanidines; Guinea Pigs; Histamin | 1999 |
Comparative study of the H2-receptor antagonists cimetidine, ranitidine, famotidine and nizatidine on the rabbit stomach fundus and sigmoid colon.
Topics: Acetylcholine; Animals; Cimetidine; Colon, Sigmoid; Famotidine; Female; Gastric Fundus; Histamine H2 | 1992 |
Effects of FRG-8701 on gastric acid secretion, gastric mucosal lesions by necrotizing agents and experimental gastric or duodenal ulcer in rats.
Topics: Acetamides; Animals; Cimetidine; Duodenal Ulcer; Famotidine; Gastric Acid; Gastric Mucosa; Guinea Pi | 1990 |
Cholinergic effects of histamine-H2 receptor antagonists partly through inhibition of acetylcholinesterase.
Topics: Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cimetidine; Famotidine; Guinea Pigs; Hist | 1986 |
Direct effects of H2-receptor antagonists on airway smooth muscle and on responses mediated by H1- and H2-receptors.
Topics: Animals; Cimetidine; Famotidine; Guinea Pigs; Histamine H2 Antagonists; In Vitro Techniques; Male; M | 1987 |
Pharmacology of the novel H2 antagonist famotidine: in vitro studies.
Topics: Animals; Famotidine; Female; Gallbladder; Gastric Acid; Gastrointestinal Motility; Histamine H2 Anta | 1986 |