famotidine has been researched along with Metastase in 12 studies
Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Outpatient intravenous IL-2 and famotidine has activity in melanoma." | 7.78 | Outpatient intravenous interleukin-2 with famotidine has activity in metastatic melanoma. ( Johnson, E; Perez, M; Quan, FM; Quan, WD, 2012) |
| "Famotidine may increase LAK activity by increasing IL-2 internalization by the IL-2 receptor on lymphocytes." | 5.35 | High-dose intensity pulse interleukin-2 with famotidine has activity in metastatic melanoma. ( King, LA; Liles, DK; Picton, M; Quan, FM; Quan, WD; Tyre, C; Walker, PR, 2008) |
| "Two (2) patients with kidney cancer have been converted to complete responders with resection of residual disease, remaining without relapse at 5+ and 20+ months." | 5.33 | Activity of continuous infusion plus pulse interleukin-2 with famotidine in patients with metastatic kidney cancer or melanoma previously treated with interleukin-2. ( Elsamaloty, HM; Ghai, V; Liles, DK; Quan, FM; Quan, WD; Ramirez, M; Vinogradov, M; Walker, PR, 2006) |
| "High-dose, continuous-infusion interleukin-2 (IL-2) followed by pulse dose and concurrent administration of famotidine has demonstrated response rates of 64% and 33% in patients with metastatic melanoma and metastatic renal cell carcinoma, respectively." | 4.84 | Nursing care of patients receiving high-dose, continuous-infusion interleukin-2 with pulse dose and famotidine. ( Quan, W; Tyre, CC, 2007) |
| " Outpatient intravenous IL-2 and famotidine has activity in melanoma." | 3.78 | Outpatient intravenous interleukin-2 with famotidine has activity in metastatic melanoma. ( Johnson, E; Perez, M; Quan, FM; Quan, WD, 2012) |
| "Paclitaxel Css values were not significantly different in individual patients when either cimetidine or famotidine preceded paclitaxel (p = 0." | 2.68 | Pretreatment H2 receptor antagonists that differ in P450 modulation activity: comparative effects on paclitaxel clearance rates and neutropenia. ( Bowling, MK; Chen, TL; Donehower, RC; McGuire, WP; Rowinsky, EK; Slichenmyer, WJ, 1995) |
| "Famotidine may increase LAK activity by increasing IL-2 internalization by the IL-2 receptor on lymphocytes." | 1.35 | High-dose intensity pulse interleukin-2 with famotidine has activity in metastatic melanoma. ( King, LA; Liles, DK; Picton, M; Quan, FM; Quan, WD; Tyre, C; Walker, PR, 2008) |
| "Famotidine may enhance LAK cytolytic ability." | 1.33 | High-dose continuous infusion plus pulse interleukin-2 and famotidine in metastatic kidney cancer. ( Khan, N; Quan, F; Quan, W; Ramirez, M; Taylor, C; Vinogradov, M, 2005) |
| "Two (2) patients with kidney cancer have been converted to complete responders with resection of residual disease, remaining without relapse at 5+ and 20+ months." | 1.33 | Activity of continuous infusion plus pulse interleukin-2 with famotidine in patients with metastatic kidney cancer or melanoma previously treated with interleukin-2. ( Elsamaloty, HM; Ghai, V; Liles, DK; Quan, FM; Quan, WD; Ramirez, M; Vinogradov, M; Walker, PR, 2006) |
| "tumor growth, secondary lung metastasis and splenocyte cytotoxicity against YAC-1 lymphoma cells (51Cr release assay)." | 1.29 | Effects of histamine type-2 receptor antagonists on indomethacin and IL-2 immunotherapy of metastasis. ( Khoo, NK; Lala, PK; Saarloos, MN, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quan, WD | 7 |
| Walker, PR | 5 |
| Picton, M | 1 |
| Quan, FM | 6 |
| King, LA | 1 |
| Tyre, C | 1 |
| Liles, DK | 4 |
| Perez, M | 1 |
| Johnson, E | 1 |
| Quan, W | 2 |
| Ramirez, M | 2 |
| Taylor, C | 1 |
| Vinogradov, M | 3 |
| Quan, F | 1 |
| Khan, N | 3 |
| Khuder, SA | 1 |
| Elsamaloty, HM | 1 |
| Ghai, V | 1 |
| Milligan, KS | 1 |
| Cuenca, RE | 1 |
| Tyre, CC | 1 |
| Slichenmyer, WJ | 1 |
| Donehower, RC | 1 |
| Chen, TL | 1 |
| Bowling, MK | 1 |
| McGuire, WP | 1 |
| Rowinsky, EK | 1 |
| Torralba, M | 1 |
| MartÃnez, A | 1 |
| Puras, A | 1 |
| Saarloos, MN | 1 |
| Khoo, NK | 1 |
| Lala, PK | 1 |
2 reviews available for famotidine and Metastase
| Article | Year |
|---|---|
Continuous infusion interleukin-2 and antihistamines in metastatic kidney cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Agents; Cimetidine; Famotidine; Histamine; Histamine H1 Antag | 2005 |
Nursing care of patients receiving high-dose, continuous-infusion interleukin-2 with pulse dose and famotidine.
Topics: Anti-Ulcer Agents; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Administration Schedule; Drug | 2007 |
4 trials available for famotidine and Metastase
| Article | Year |
|---|---|
High-dose intensity pulse interleukin-2 with famotidine in metastatic kidney cancer.
Topics: Aged; Cytokine-Induced Killer Cells; Disease Progression; Drug Administration Schedule; Drug Interac | 2009 |
Continuous infusion interleukin-2 and famotidine in metastatic kidney cancer.
Topics: Adult; Aged; Drug Administration Schedule; Drug Synergism; Famotidine; Female; Humans; Immunotherapy | 2006 |
Continuous infusion interleukin-2 and intravenous famotidine in metastatic melanoma.
Topics: Adult; Aged; Drug Therapy, Combination; Famotidine; Female; Humans; Infusions, Intravenous; Interleu | 2006 |
Pretreatment H2 receptor antagonists that differ in P450 modulation activity: comparative effects on paclitaxel clearance rates and neutropenia.
Topics: Adult; Aged; Cimetidine; Cross-Over Studies; Cytochrome P-450 Enzyme System; Famotidine; Female; His | 1995 |
6 other studies available for famotidine and Metastase
| Article | Year |
|---|---|
High-dose intensity pulse interleukin-2 with famotidine has activity in metastatic melanoma.
Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Disease Progression; Famotidine; Female; Humans; | 2008 |
Outpatient intravenous interleukin-2 with famotidine has activity in metastatic melanoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Famotidine; Female; | 2012 |
High-dose continuous infusion plus pulse interleukin-2 and famotidine in metastatic kidney cancer.
Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Famotidine; Female; Histamine H2 Anta | 2005 |
Activity of continuous infusion plus pulse interleukin-2 with famotidine in patients with metastatic kidney cancer or melanoma previously treated with interleukin-2.
Topics: Aged; Drug Administration Schedule; Drug Synergism; Famotidine; Female; Humans; Immunotherapy; Infus | 2006 |
[Leukocytoclastic vasculitis and leiomyosarcoma].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Famotidine; Foot Diseases; Histiocytoma, Benign Fibrous; Hu | 1993 |
Effects of histamine type-2 receptor antagonists on indomethacin and IL-2 immunotherapy of metastasis.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Cimetidine; Famotidine; Female; Histamine H2 Antago | 1993 |