famotidine has been researched along with Hematochezia in 30 studies
Famotidine: A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
Hematochezia: The passage of bright red blood from the rectum. The blood may or may not be mixed with formed stool in the form of blood, blood clots, bloody stool or diarrhea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Little is known about the efficacy of proton pump inhibitors compared with H(2) receptor antagonists in preventing adverse upper gastrointestinal complications in patients with acute coronary syndrome (ACS) or ST elevation myocardial infarction (STEMI) receiving aspirin, clopidogrel, and enoxaparin or thrombolytics." | 9.16 | Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction. ( Chan, K; Chu, WM; Keung, KK; Kng, C; Kwan, A; Lam, KF; Lau, YK; Li, A; Ng, FH; Tunggal, P; Wong, BC, 2012) |
| "Little is known about the efficacy of H(2)-receptor antagonists in preventing recurrence of aspirin-related peptic ulcers." | 9.14 | Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions. ( Chan, P; Chu, WM; Kng, C; Kwan, A; Lam, KF; Lau, YK; Ling, YH; Ng, FH; Wong, BC; Wong, SY; Yuen, WC, 2010) |
| "We retrospectively investigated the efficacy of high dose omeprazole compared to a combined therapy of famotidine, pirenzepine and antacid for acute upper gastrointestinal hemorrhage (AUGIH) also adjuvant to endoscopic injection therapy if indicated." | 7.69 | [High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison]. ( Busam, J; Garbe, WE, 1994) |
| "7% of the patients in the 10- and 20-mg dosage groups, respectively, did not have evidence of erosions or hemorrhages, compared with 73% of patients in the 5-mg group." | 6.66 | Famotidine in the treatment of gastritis. ( Miwa, T; Miyoshi, A, 1987) |
| "Little is known about the efficacy of proton pump inhibitors compared with H(2) receptor antagonists in preventing adverse upper gastrointestinal complications in patients with acute coronary syndrome (ACS) or ST elevation myocardial infarction (STEMI) receiving aspirin, clopidogrel, and enoxaparin or thrombolytics." | 5.16 | Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction. ( Chan, K; Chu, WM; Keung, KK; Kng, C; Kwan, A; Lam, KF; Lau, YK; Li, A; Ng, FH; Tunggal, P; Wong, BC, 2012) |
| "Little is known about the efficacy of H(2)-receptor antagonists in preventing recurrence of aspirin-related peptic ulcers." | 5.14 | Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions. ( Chan, P; Chu, WM; Kng, C; Kwan, A; Lam, KF; Lau, YK; Ling, YH; Ng, FH; Wong, BC; Wong, SY; Yuen, WC, 2010) |
| "We retrospectively investigated the efficacy of high dose omeprazole compared to a combined therapy of famotidine, pirenzepine and antacid for acute upper gastrointestinal hemorrhage (AUGIH) also adjuvant to endoscopic injection therapy if indicated." | 3.69 | [High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison]. ( Busam, J; Garbe, WE, 1994) |
| "Famotidine was well tolerated." | 2.79 | Famotidine as a radioprotector for rectal mucosa in prostate cancer patients treated with radiotherapy: phase I/II randomized placebo-controlled trial. ( Mofid, B; Mozdarani, H; Razzaghdoust, A, 2014) |
| " Subjects underwent EMR with circumferential mucosal incision assisted by submucosal injection of sodium hyaluronate (EMRSH), followed by IV or oral (PO) administration of famotidine at a dosage of 40 mg/day for 2 days." | 2.71 | Comparison of hemostatic effects by route of H2 receptor antagonist administration following endoscopic mucosal resection in patients with neoplastic gastric lesions. ( Ajibe, H; Hanatsuka, K; Hirasawa, T; Kawata, H; Kita, H; Osawa, H; Satoh, K; Satoh, Y; Sugano, K; Sunada, F; Sunada, K; Yamamoto, H; Yoshizawa, M, 2005) |
| "7% of the patients in the 10- and 20-mg dosage groups, respectively, did not have evidence of erosions or hemorrhages, compared with 73% of patients in the 5-mg group." | 2.66 | Famotidine in the treatment of gastritis. ( Miwa, T; Miyoshi, A, 1987) |
| " Dosage requirements vary according to age and clinical condition, and children require a relatively higher drug dosage (mg/kg) than adults." | 2.39 | Do H2 receptor antagonists have a therapeutic role in childhood? ( Kelly, DA, 1994) |
| "Although acid suppressants are needed to attenuate gastrointestinal bleeding (GIB) after percutaneous coronary intervention (PCI), pharmacodynamic interaction between clopidogrel and proton pump inhibitor (PPI) can increase the risk of high platelet reactivity (HPR)." | 1.56 | Influence of rabeprazole and famotidine on pharmacodynamic profile of dual antiplatelet therapy in clopidogrel-sensitive patients: The randomized, prospective, PROTECT trial. ( Ahn, JH; Bae, JS; Hwang, JY; Hwang, SJ; Jang, JY; Jeong, YH; Kang, MG; Kim, KH; Koh, JS; Kwak, CH; Park, JR; Park, Y, 2020) |
| "Lansoprazole was more potent than omeprazole, famotidine and ranitidine in inhibiting gastric mucosal lesions and hemorrhagic shock- or stress-induced bleeding." | 1.29 | [Effects of intravenous lansoprazole on acute gastric mucosal lesions and acid secretion]. ( Asano, S; Inada, I; Inatomi, N; Murakami, I; Satoh, H, 1996) |
| "This study was designed to establish appropriate dosing requirements for intravenous use of famotidine, a new H2-receptor antagonist, in pediatric patients." | 1.28 | Suppression of gastric acid secretion by intravenous administration of famotidine in children. ( Davis, PM; Hyams, JS; Treem, WR, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (13.33) | 18.7374 |
| 1990's | 9 (30.00) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 8 (26.67) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Tseng, ZF | 1 |
| Hsu, PI | 1 |
| Peng, NJ | 1 |
| Kao, SS | 1 |
| Tsay, FW | 1 |
| Cheng, JS | 1 |
| Chen, WC | 1 |
| Tsai, KF | 1 |
| Tang, SY | 1 |
| Chuah, SK | 1 |
| Shie, CB | 1 |
| Matsueda, K | 1 |
| Toyokawa, T | 1 |
| Sakata, M | 1 |
| Fujita, I | 1 |
| Horii, J | 1 |
| Abe, Y | 1 |
| Araki, T | 1 |
| Ahn, JH | 1 |
| Park, Y | 1 |
| Bae, JS | 1 |
| Jang, JY | 1 |
| Kim, KH | 1 |
| Kang, MG | 1 |
| Koh, JS | 1 |
| Park, JR | 1 |
| Hwang, SJ | 1 |
| Kwak, CH | 1 |
| Hwang, JY | 1 |
| Jeong, YH | 1 |
| Vagner, DO | 1 |
| Shlyk, IV | 1 |
| Verbitskiĭ, VG | 1 |
| Razzaghdoust, A | 1 |
| Mozdarani, H | 1 |
| Mofid, B | 1 |
| Ng, FH | 2 |
| Wong, SY | 1 |
| Lam, KF | 2 |
| Chu, WM | 2 |
| Chan, P | 1 |
| Ling, YH | 1 |
| Kng, C | 2 |
| Yuen, WC | 1 |
| Lau, YK | 2 |
| Kwan, A | 2 |
| Wong, BC | 2 |
| Brophy, GM | 1 |
| Brackbill, ML | 1 |
| Bidwell, KL | 1 |
| Brophy, DF | 1 |
| Tunggal, P | 1 |
| Li, A | 1 |
| Chan, K | 1 |
| Keung, KK | 1 |
| Sakurada, T | 1 |
| Kawashima, J | 1 |
| Ariyama, S | 1 |
| Kani, K | 1 |
| Takabayashi, H | 1 |
| Ohno, S | 1 |
| Kato, S | 1 |
| Yakabi, K | 1 |
| Takayama, S | 1 |
| Izuhara, C | 1 |
| Yamada, N | 1 |
| Yamanaka, S | 1 |
| Hashimoto, E | 1 |
| Kaneko, S | 1 |
| Takeuchi, K | 1 |
| Chen, FB | 1 |
| Huang, XL | 1 |
| Chen, J | 1 |
| Wu, M | 1 |
| Wang, J | 1 |
| Zhou, X | 1 |
| Yamaguchi, Y | 1 |
| Katsumi, N | 1 |
| Tauchi, M | 1 |
| Toki, M | 1 |
| Nakamura, K | 1 |
| Aoki, K | 1 |
| Morita, Y | 1 |
| Miura, M | 1 |
| Morozumi, K | 1 |
| Ishida, H | 1 |
| Takahashi, S | 1 |
| Satoh, K | 1 |
| Yamamoto, H | 1 |
| Kawata, H | 1 |
| Osawa, H | 1 |
| Hanatsuka, K | 1 |
| Kita, H | 1 |
| Sunada, K | 1 |
| Hirasawa, T | 1 |
| Yoshizawa, M | 1 |
| Ajibe, H | 1 |
| Satoh, Y | 1 |
| Sunada, F | 1 |
| Sugano, K | 1 |
| Gon, S | 1 |
| Irie, Y | 1 |
| Takahashi, M | 1 |
| Ye, BD | 1 |
| Cheon, JH | 1 |
| Choi, KD | 1 |
| Kim, SG | 1 |
| Kim, JS | 1 |
| Jung, HC | 1 |
| Song, IS | 1 |
| Jeong, HK | 1 |
| Park, CH | 1 |
| Jun, CH | 1 |
| Lee, GH | 1 |
| Kim, HI | 1 |
| Kim, HS | 1 |
| Choi, SK | 1 |
| Rew, JS | 1 |
| Kelly, DA | 1 |
| Watanabe, H | 1 |
| Yamada, S | 1 |
| Yoshikawa, N | 1 |
| Kasanuki, J | 1 |
| Yoshida, S | 1 |
| Tokunaga, A | 1 |
| Busam, J | 1 |
| Garbe, WE | 1 |
| Inatomi, N | 2 |
| Murakami, I | 2 |
| Asano, S | 2 |
| Inada, I | 1 |
| Satoh, H | 2 |
| Yukishige, K | 1 |
| Nagaya, H | 1 |
| Aanpreung, P | 1 |
| Vanprapar, N | 1 |
| Susiva, C | 1 |
| Parkpreaw, C | 1 |
| Boonyachart, C | 1 |
| Gonzales-Rosales, F | 1 |
| Walsh, D | 1 |
| Burkons, L | 1 |
| Burkons, J | 1 |
| Horvitz, HR | 1 |
| Shlevkov, BA | 1 |
| Abramova, LA | 1 |
| Toguzova, DA | 1 |
| Treem, WR | 1 |
| Davis, PM | 1 |
| Hyams, JS | 1 |
| Karlstadt, RG | 1 |
| Palmer, RH | 1 |
| Daneshmend, TK | 1 |
| Prichard, PJ | 1 |
| Bhaskar, NK | 1 |
| Millns, PJ | 1 |
| Hawkey, CJ | 1 |
| Saigenji, K | 1 |
| Fukutomi, H | 1 |
| Nakazawa, S | 1 |
| Miwa, T | 1 |
| Miyoshi, A | 1 |
| Echizen, H | 1 |
| Shoda, R | 1 |
| Umeda, N | 1 |
| Ishizaki, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of H2 Receptor Antagonist in Prevention of Thienopyridine-related Peptic Ulcer[NCT02418312] | 228 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
| Pantoprazole Versus Famotidine for the Prevention of Recurrent Peptic Ulcers in Thienopyridine Users - a Double-blind Randomized Controlled Trial[NCT02551744] | 101 participants (Actual) | Interventional | 2012-07-31 | Completed | |||
| Famotidine Compared With Esomeprazole in the Prevention of Ulcer Complications in Patients With Acute Coronary Syndrome or Myocardial Infarction[NCT00683111] | Phase 4 | 500 participants (Anticipated) | Interventional | 2008-07-31 | Completed | ||
| Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study[NCT02081404] | 98 participants (Actual) | Interventional | 2009-03-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Follow-up endoscopy was performed at the end of the 6th month (NCT02418312)
Timeframe: 6 months
| Intervention | participants (Number) |
|---|---|
| Histamine-2 Receptor Antagonist Group | 106 |
| Placebo Group | 101 |
Follow-up endoscopy was performed at the end of the 6th month (NCT02551744)
Timeframe: six month
| Intervention | participants (Number) |
|---|---|
| Proton Pump Inhibitor Group | 1 |
| Histamine-2 Receptor Antagonist Group | 7 |
1 review available for famotidine and Hematochezia
| Article | Year |
|---|---|
Do H2 receptor antagonists have a therapeutic role in childhood?
Topics: Adolescent; Child; Child, Preschool; Cimetidine; Cystic Fibrosis; Drug Interactions; Famotidine; Gas | 1994 |
13 trials available for famotidine and Hematochezia
| Article | Year |
|---|---|
Omeprazole vs famotidine for the prevention of gastroduodenal injury in high-risk users of low-dose aspirin: A randomized controlled trial.
Topics: Aged; Aged, 80 and over; Aspirin; Famotidine; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; H | 2021 |
Famotidine as a radioprotector for rectal mucosa in prostate cancer patients treated with radiotherapy: phase I/II randomized placebo-controlled trial.
Topics: Administration, Oral; Aged; Aged, 80 and over; Dose Fractionation, Radiation; Dose-Response Relation | 2014 |
Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non- | 2010 |
Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non- | 2010 |
Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non- | 2010 |
Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non- | 2010 |
Prospective, randomized comparison of lansoprazole suspension, and intermittent intravenous famotidine on gastric pH and acid production in critically ill neurosurgical patients.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Critical Illness; Famotidine; Fem | 2010 |
Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction.
Topics: Acute Coronary Syndrome; Aged; Anti-Ulcer Agents; Aspirin; Chi-Square Distribution; Clopidogrel; Dou | 2012 |
Comparison of adjuvant therapies by an H2-receptor antagonist and a proton pump inhibitor after endoscopic treatment in hemostatic management of bleeding gastroduodenal ulcers.
Topics: Chemotherapy, Adjuvant; Enzyme Inhibitors; Famotidine; Female; Gastrointestinal Hemorrhage; Hemostas | 2012 |
A prospective randomized trial of either famotidine or omeprazole for the prevention of bleeding after endoscopic mucosal resection and the healing of endoscopic mucosal resection-induced ulceration.
Topics: Aged; Anti-Ulcer Agents; Cost-Benefit Analysis; Endoscopy, Gastrointestinal; Famotidine; Female; Gas | 2005 |
Comparison of hemostatic effects by route of H2 receptor antagonist administration following endoscopic mucosal resection in patients with neoplastic gastric lesions.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Administration, Oral; Aged; Endoscopy, Gastrointestinal; Fam | 2005 |
Omeprazole may be superior to famotidine in the management of iatrogenic ulcer after endoscopic mucosal resection: a prospective randomized controlled trial.
Topics: Anti-Ulcer Agents; Famotidine; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Hum | 2006 |
A prospective randomized trial of either famotidine or pantoprazole for the prevention of bleeding after endoscopic submucosal dissection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Ulcer Agents; Dissection; Famotidine; Female; Ga | 2007 |
A randomized clinical trial comparing the efficacy of ranitidine and famotidine on intragastric acidity in critically ill pediatric patients.
Topics: Analysis of Variance; Child; Child, Preschool; Critical Illness; Famotidine; Female; Gastrointestina | 1998 |
Use of microbleeding and an ultrathin endoscope to assess gastric mucosal protection by famotidine.
Topics: Adolescent; Adult; Aspirin; Double-Blind Method; Famotidine; Female; Gastric Mucosa; Gastrointestina | 1989 |
Famotidine in the treatment of gastritis.
Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Famoti | 1987 |
16 other studies available for famotidine and Hematochezia
| Article | Year |
|---|---|
Hemorrhagic Stress-induced Gastric Ulcer in a Healthy Toddler.
Topics: Acute Disease; Endoscopy; Famotidine; Female; Gastrointestinal Hemorrhage; Humans; Infant; Peptic Ul | 2018 |
Influence of rabeprazole and famotidine on pharmacodynamic profile of dual antiplatelet therapy in clopidogrel-sensitive patients: The randomized, prospective, PROTECT trial.
Topics: Aged; Clopidogrel; Drug Interactions; Famotidine; Female; Gastrointestinal Hemorrhage; Humans; Male; | 2020 |
[Risk factors of gastroduodenal bleeding in patients with severe burns].
Topics: Anti-Ulcer Agents; Burns; Duodenum; Famotidine; Gastrointestinal Hemorrhage; Humans; Outcome and Pro | 2013 |
A new model of gastric bleeding induced in rats by aspirin plus clopidogrel under stimulation of acid secretion. Prophylactic effects of antiulcer drugs.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Drug Interactions; Famotidine; Gastric Acid; Gastr | 2012 |
[Effect and safety of famotidine for therapy of gastrointestinal bleeding in children].
Topics: Child; Famotidine; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans | 2005 |
Effects of rabeprazole or famotidine during cardiac surgery on perioperative gastric and esophageal pH readings.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; | 2006 |
Effect of famotidine on gastric mucosal lesions induced by gold thioglucose in rats.
Topics: Animals; Aurothioglucose; Disease Models, Animal; Famotidine; Gastric Acid; Gastric Juice; Gastric M | 1993 |
[High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison].
Topics: Aged; Aged, 80 and over; Aluminum Hydroxide; Antacids; Dose-Response Relationship, Drug; Drug Admini | 1994 |
[Effects of intravenous lansoprazole on acute gastric mucosal lesions and acid secretion].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Animals; Anti-Ulcer Agents; Famotidine; Gast | 1996 |
[Effects of lansoprazole on indomethacin-induced gastric bleeding and mucosal lesions in rats].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Dru | 1996 |
Chronic bleeding secondary to an unresectable duodenal adenocarcinoma controlled with sucralfate and famotidine.
Topics: Adenocarcinoma; Aged; Duodenal Neoplasms; Famotidine; Female; Gastrointestinal Agents; Gastrointesti | 1998 |
[Experience in clinical use of quamatel in upper gastrointestinal hemorrhage].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Duodenal Ulcer; Famotidine; Female; Gastroin | 2001 |
Suppression of gastric acid secretion by intravenous administration of famotidine in children.
Topics: Child, Preschool; Drug Evaluation; Famotidine; Female; Gastric Acid; Gastric Acidity Determination; | 1991 |
Continuous infusion H2-receptor therapy.
Topics: Cimetidine; Famotidine; Gastrointestinal Hemorrhage; Humans; Research | 1990 |
Famotidine: postmarketing clinical experience.
Topics: Adult; Famotidine; Female; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Histamine H2 Anta | 1987 |
Plasma famotidine concentration versus intragastric pH in patients with upper gastrointestinal bleeding and in healthy subjects.
Topics: Adult; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Gastric Acidity Determina | 1988 |